Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons

In the hypothalamus, the arcuate nucleus (ARC) contains AgRP-neurons that regulate energy balance as well as GHRH-neurons that regulate linear growth. Here, the authors looked at how the transcription factors Dlx1/2 and Otp link development of AgRP- and GHRH-neurons.

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Autores principales:	Bora Lee, Janghyun Kim, Taekyeong An, Sangsoo Kim, Esha M. Patel, Jacob Raber, Soo-Kyung Lee, Seunghee Lee, Jae W. Lee
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/87bb4bf21bac41069518ebbc205fec67
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spelling	oai:doaj.org-article:87bb4bf21bac41069518ebbc205fec672021-12-02T15:34:19ZDlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons10.1038/s41467-018-04377-42041-1723https://doaj.org/article/87bb4bf21bac41069518ebbc205fec672018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04377-4https://doaj.org/toc/2041-1723In the hypothalamus, the arcuate nucleus (ARC) contains AgRP-neurons that regulate energy balance as well as GHRH-neurons that regulate linear growth. Here, the authors looked at how the transcription factors Dlx1/2 and Otp link development of AgRP- and GHRH-neurons.Bora LeeJanghyun KimTaekyeong AnSangsoo KimEsha M. PatelJacob RaberSoo-Kyung LeeSeunghee LeeJae W. LeeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Bora Lee Janghyun Kim Taekyeong An Sangsoo Kim Esha M. Patel Jacob Raber Soo-Kyung Lee Seunghee Lee Jae W. Lee Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons
description	In the hypothalamus, the arcuate nucleus (ARC) contains AgRP-neurons that regulate energy balance as well as GHRH-neurons that regulate linear growth. Here, the authors looked at how the transcription factors Dlx1/2 and Otp link development of AgRP- and GHRH-neurons.
format	article
author	Bora Lee Janghyun Kim Taekyeong An Sangsoo Kim Esha M. Patel Jacob Raber Soo-Kyung Lee Seunghee Lee Jae W. Lee
author_facet	Bora Lee Janghyun Kim Taekyeong An Sangsoo Kim Esha M. Patel Jacob Raber Soo-Kyung Lee Seunghee Lee Jae W. Lee
author_sort	Bora Lee
title	Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons
title_short	Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons
title_full	Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons
title_fullStr	Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons
title_full_unstemmed	Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons
title_sort	dlx1/2 and otp coordinate the production of hypothalamic ghrh- and agrp-neurons
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/87bb4bf21bac41069518ebbc205fec67
work_keys_str_mv	AT boralee dlx12andotpcoordinatetheproductionofhypothalamicghrhandagrpneurons AT janghyunkim dlx12andotpcoordinatetheproductionofhypothalamicghrhandagrpneurons AT taekyeongan dlx12andotpcoordinatetheproductionofhypothalamicghrhandagrpneurons AT sangsookim dlx12andotpcoordinatetheproductionofhypothalamicghrhandagrpneurons AT eshampatel dlx12andotpcoordinatetheproductionofhypothalamicghrhandagrpneurons AT jacobraber dlx12andotpcoordinatetheproductionofhypothalamicghrhandagrpneurons AT sookyunglee dlx12andotpcoordinatetheproductionofhypothalamicghrhandagrpneurons AT seungheelee dlx12andotpcoordinatetheproductionofhypothalamicghrhandagrpneurons AT jaewlee dlx12andotpcoordinatetheproductionofhypothalamicghrhandagrpneurons
_version_	1718386847847022592

Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons

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