High-flexibility combinatorial peptide synthesis with laser-based transfer of monomers in solid matrix material

Peptide arrays are used in areas such as measuring protein-protein interactions, but achieving high density in synthesis is challenging. Here, the authors report a method for the combinatorial synthesis of high density peptides arrays by laser driven sequential transfer of monomers onto acceptor sur...

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Autores principales: Felix F. Loeffler, Tobias C. Foertsch, Roman Popov, Daniela S. Mattes, Martin Schlageter, Martyna Sedlmayr, Barbara Ridder, Florian-Xuan Dang, Clemens von Bojničić-Kninski, Laura K. Weber, Andrea Fischer, Juliane Greifenstein, Valentina Bykovskaya, Ivan Buliev, F. Ralf Bischoff, Lothar Hahn, Michael A. R. Meier, Stefan Bräse, Annie K. Powell, Teodor Silviu Balaban, Frank Breitling, Alexander Nesterov-Mueller
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/87c83875d9e247549c186e22093d2d6b
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spelling oai:doaj.org-article:87c83875d9e247549c186e22093d2d6b2021-12-02T16:49:26ZHigh-flexibility combinatorial peptide synthesis with laser-based transfer of monomers in solid matrix material10.1038/ncomms118442041-1723https://doaj.org/article/87c83875d9e247549c186e22093d2d6b2016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11844https://doaj.org/toc/2041-1723Peptide arrays are used in areas such as measuring protein-protein interactions, but achieving high density in synthesis is challenging. Here, the authors report a method for the combinatorial synthesis of high density peptides arrays by laser driven sequential transfer of monomers onto acceptor surfaces.Felix F. LoefflerTobias C. FoertschRoman PopovDaniela S. MattesMartin SchlageterMartyna SedlmayrBarbara RidderFlorian-Xuan DangClemens von Bojničić-KninskiLaura K. WeberAndrea FischerJuliane GreifensteinValentina BykovskayaIvan BulievF. Ralf BischoffLothar HahnMichael A. R. MeierStefan BräseAnnie K. PowellTeodor Silviu BalabanFrank BreitlingAlexander Nesterov-MuellerNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Felix F. Loeffler
Tobias C. Foertsch
Roman Popov
Daniela S. Mattes
Martin Schlageter
Martyna Sedlmayr
Barbara Ridder
Florian-Xuan Dang
Clemens von Bojničić-Kninski
Laura K. Weber
Andrea Fischer
Juliane Greifenstein
Valentina Bykovskaya
Ivan Buliev
F. Ralf Bischoff
Lothar Hahn
Michael A. R. Meier
Stefan Bräse
Annie K. Powell
Teodor Silviu Balaban
Frank Breitling
Alexander Nesterov-Mueller
High-flexibility combinatorial peptide synthesis with laser-based transfer of monomers in solid matrix material
description Peptide arrays are used in areas such as measuring protein-protein interactions, but achieving high density in synthesis is challenging. Here, the authors report a method for the combinatorial synthesis of high density peptides arrays by laser driven sequential transfer of monomers onto acceptor surfaces.
format article
author Felix F. Loeffler
Tobias C. Foertsch
Roman Popov
Daniela S. Mattes
Martin Schlageter
Martyna Sedlmayr
Barbara Ridder
Florian-Xuan Dang
Clemens von Bojničić-Kninski
Laura K. Weber
Andrea Fischer
Juliane Greifenstein
Valentina Bykovskaya
Ivan Buliev
F. Ralf Bischoff
Lothar Hahn
Michael A. R. Meier
Stefan Bräse
Annie K. Powell
Teodor Silviu Balaban
Frank Breitling
Alexander Nesterov-Mueller
author_facet Felix F. Loeffler
Tobias C. Foertsch
Roman Popov
Daniela S. Mattes
Martin Schlageter
Martyna Sedlmayr
Barbara Ridder
Florian-Xuan Dang
Clemens von Bojničić-Kninski
Laura K. Weber
Andrea Fischer
Juliane Greifenstein
Valentina Bykovskaya
Ivan Buliev
F. Ralf Bischoff
Lothar Hahn
Michael A. R. Meier
Stefan Bräse
Annie K. Powell
Teodor Silviu Balaban
Frank Breitling
Alexander Nesterov-Mueller
author_sort Felix F. Loeffler
title High-flexibility combinatorial peptide synthesis with laser-based transfer of monomers in solid matrix material
title_short High-flexibility combinatorial peptide synthesis with laser-based transfer of monomers in solid matrix material
title_full High-flexibility combinatorial peptide synthesis with laser-based transfer of monomers in solid matrix material
title_fullStr High-flexibility combinatorial peptide synthesis with laser-based transfer of monomers in solid matrix material
title_full_unstemmed High-flexibility combinatorial peptide synthesis with laser-based transfer of monomers in solid matrix material
title_sort high-flexibility combinatorial peptide synthesis with laser-based transfer of monomers in solid matrix material
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/87c83875d9e247549c186e22093d2d6b
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