The deep and slow breathing characterizing rest favors brain respiratory-drive

Abstract A respiration-locked activity in the olfactory brain, mainly originating in the mechano-sensitivity of olfactory sensory neurons to air pressure, propagates from the olfactory bulb to the rest of the brain. Interestingly, changes in nasal airflow rate result in reorganization of olfactory b...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Baptiste Girin, Maxime Juventin, Samuel Garcia, Laura Lefèvre, Corine Amat, Nicolas Fourcaud-Trocmé, Nathalie Buonviso
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
R
Q
Acceso en línea:https://doaj.org/article/87ca285147e446f682c4fbaa2e987395
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:87ca285147e446f682c4fbaa2e987395
record_format dspace
spelling oai:doaj.org-article:87ca285147e446f682c4fbaa2e9873952021-12-02T13:26:50ZThe deep and slow breathing characterizing rest favors brain respiratory-drive10.1038/s41598-021-86525-32045-2322https://doaj.org/article/87ca285147e446f682c4fbaa2e9873952021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-86525-3https://doaj.org/toc/2045-2322Abstract A respiration-locked activity in the olfactory brain, mainly originating in the mechano-sensitivity of olfactory sensory neurons to air pressure, propagates from the olfactory bulb to the rest of the brain. Interestingly, changes in nasal airflow rate result in reorganization of olfactory bulb response. By leveraging spontaneous variations of respiratory dynamics during natural conditions, we investigated whether respiratory drive also varies with nasal airflow movements. We analyzed local field potential activity relative to respiratory signal in various brain regions during waking and sleep states. We found that respiration regime was state-specific, and that quiet waking was the only vigilance state during which all the recorded structures can be respiration-driven whatever the respiratory frequency. Using CO2-enriched air to alter respiratory regime associated to each state and a respiratory cycle based analysis, we evidenced that the large and strong brain drive observed during quiet waking was related to an optimal trade-off between depth and duration of inspiration in the respiratory pattern, characterizing this specific state. These results show for the first time that changes in respiration regime affect cortical dynamics and that the respiratory regime associated with rest is optimal for respiration to drive the brain.Baptiste GirinMaxime JuventinSamuel GarciaLaura LefèvreCorine AmatNicolas Fourcaud-TrocméNathalie BuonvisoNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Baptiste Girin
Maxime Juventin
Samuel Garcia
Laura Lefèvre
Corine Amat
Nicolas Fourcaud-Trocmé
Nathalie Buonviso
The deep and slow breathing characterizing rest favors brain respiratory-drive
description Abstract A respiration-locked activity in the olfactory brain, mainly originating in the mechano-sensitivity of olfactory sensory neurons to air pressure, propagates from the olfactory bulb to the rest of the brain. Interestingly, changes in nasal airflow rate result in reorganization of olfactory bulb response. By leveraging spontaneous variations of respiratory dynamics during natural conditions, we investigated whether respiratory drive also varies with nasal airflow movements. We analyzed local field potential activity relative to respiratory signal in various brain regions during waking and sleep states. We found that respiration regime was state-specific, and that quiet waking was the only vigilance state during which all the recorded structures can be respiration-driven whatever the respiratory frequency. Using CO2-enriched air to alter respiratory regime associated to each state and a respiratory cycle based analysis, we evidenced that the large and strong brain drive observed during quiet waking was related to an optimal trade-off between depth and duration of inspiration in the respiratory pattern, characterizing this specific state. These results show for the first time that changes in respiration regime affect cortical dynamics and that the respiratory regime associated with rest is optimal for respiration to drive the brain.
format article
author Baptiste Girin
Maxime Juventin
Samuel Garcia
Laura Lefèvre
Corine Amat
Nicolas Fourcaud-Trocmé
Nathalie Buonviso
author_facet Baptiste Girin
Maxime Juventin
Samuel Garcia
Laura Lefèvre
Corine Amat
Nicolas Fourcaud-Trocmé
Nathalie Buonviso
author_sort Baptiste Girin
title The deep and slow breathing characterizing rest favors brain respiratory-drive
title_short The deep and slow breathing characterizing rest favors brain respiratory-drive
title_full The deep and slow breathing characterizing rest favors brain respiratory-drive
title_fullStr The deep and slow breathing characterizing rest favors brain respiratory-drive
title_full_unstemmed The deep and slow breathing characterizing rest favors brain respiratory-drive
title_sort deep and slow breathing characterizing rest favors brain respiratory-drive
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/87ca285147e446f682c4fbaa2e987395
work_keys_str_mv AT baptistegirin thedeepandslowbreathingcharacterizingrestfavorsbrainrespiratorydrive
AT maximejuventin thedeepandslowbreathingcharacterizingrestfavorsbrainrespiratorydrive
AT samuelgarcia thedeepandslowbreathingcharacterizingrestfavorsbrainrespiratorydrive
AT lauralefevre thedeepandslowbreathingcharacterizingrestfavorsbrainrespiratorydrive
AT corineamat thedeepandslowbreathingcharacterizingrestfavorsbrainrespiratorydrive
AT nicolasfourcaudtrocme thedeepandslowbreathingcharacterizingrestfavorsbrainrespiratorydrive
AT nathaliebuonviso thedeepandslowbreathingcharacterizingrestfavorsbrainrespiratorydrive
AT baptistegirin deepandslowbreathingcharacterizingrestfavorsbrainrespiratorydrive
AT maximejuventin deepandslowbreathingcharacterizingrestfavorsbrainrespiratorydrive
AT samuelgarcia deepandslowbreathingcharacterizingrestfavorsbrainrespiratorydrive
AT lauralefevre deepandslowbreathingcharacterizingrestfavorsbrainrespiratorydrive
AT corineamat deepandslowbreathingcharacterizingrestfavorsbrainrespiratorydrive
AT nicolasfourcaudtrocme deepandslowbreathingcharacterizingrestfavorsbrainrespiratorydrive
AT nathaliebuonviso deepandslowbreathingcharacterizingrestfavorsbrainrespiratorydrive
_version_ 1718393043385581568