En route to dynamic life processes by SNARE-mediated fusion of polymer and hybrid membranes

En route to dynamic life processes by SNARE-mediated fusion of polymer and hybrid membranes

A variety of artificial cells springs from the functionalization of liposomes with proteins but these models suffer from low durability without repair and replenishment mechanisms. Here, the authors show that synthetic amphiphile membranes undergo SNARE-mediated fusion, and determine bending rigidit...

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Autores principales: Lado Otrin, Agata Witkowska, Nika Marušič, Ziliang Zhao, Rafael B. Lira, Fotis L. Kyrilis, Farzad Hamdi, Ivan Ivanov, Reinhard Lipowsky, Panagiotis L. Kastritis, Rumiana Dimova, Kai Sundmacher, Reinhard Jahn, Tanja Vidaković-Koch
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/87cfa0761f1749479e110459d224a55d
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spelling oai:doaj.org-article:87cfa0761f1749479e110459d224a55d2021-12-02T18:01:12ZEn route to dynamic life processes by SNARE-mediated fusion of polymer and hybrid membranes10.1038/s41467-021-25294-z2041-1723https://doaj.org/article/87cfa0761f1749479e110459d224a55d2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25294-zhttps://doaj.org/toc/2041-1723A variety of artificial cells springs from the functionalization of liposomes with proteins but these models suffer from low durability without repair and replenishment mechanisms. Here, the authors show that synthetic amphiphile membranes undergo SNARE-mediated fusion, and determine bending rigidity and pore edge tension as key parameters for fusion.Lado OtrinAgata WitkowskaNika MarušičZiliang ZhaoRafael B. LiraFotis L. KyrilisFarzad HamdiIvan IvanovReinhard LipowskyPanagiotis L. KastritisRumiana DimovaKai SundmacherReinhard JahnTanja Vidaković-KochNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lado Otrin
Agata Witkowska
Nika Marušič
Ziliang Zhao
Rafael B. Lira
Fotis L. Kyrilis
Farzad Hamdi
Ivan Ivanov
Reinhard Lipowsky
Panagiotis L. Kastritis
Rumiana Dimova
Kai Sundmacher
Reinhard Jahn
Tanja Vidaković-Koch
En route to dynamic life processes by SNARE-mediated fusion of polymer and hybrid membranes
description A variety of artificial cells springs from the functionalization of liposomes with proteins but these models suffer from low durability without repair and replenishment mechanisms. Here, the authors show that synthetic amphiphile membranes undergo SNARE-mediated fusion, and determine bending rigidity and pore edge tension as key parameters for fusion.
format article
author Lado Otrin
Agata Witkowska
Nika Marušič
Ziliang Zhao
Rafael B. Lira
Fotis L. Kyrilis
Farzad Hamdi
Ivan Ivanov
Reinhard Lipowsky
Panagiotis L. Kastritis
Rumiana Dimova
Kai Sundmacher
Reinhard Jahn
Tanja Vidaković-Koch
author_facet Lado Otrin
Agata Witkowska
Nika Marušič
Ziliang Zhao
Rafael B. Lira
Fotis L. Kyrilis
Farzad Hamdi
Ivan Ivanov
Reinhard Lipowsky
Panagiotis L. Kastritis
Rumiana Dimova
Kai Sundmacher
Reinhard Jahn
Tanja Vidaković-Koch
author_sort Lado Otrin
title En route to dynamic life processes by SNARE-mediated fusion of polymer and hybrid membranes
title_short En route to dynamic life processes by SNARE-mediated fusion of polymer and hybrid membranes
title_full En route to dynamic life processes by SNARE-mediated fusion of polymer and hybrid membranes
title_fullStr En route to dynamic life processes by SNARE-mediated fusion of polymer and hybrid membranes
title_full_unstemmed En route to dynamic life processes by SNARE-mediated fusion of polymer and hybrid membranes
title_sort en route to dynamic life processes by snare-mediated fusion of polymer and hybrid membranes
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/87cfa0761f1749479e110459d224a55d
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