Endothelialization of arterial vascular grafts by circulating monocytes

Acellular tissue engineered vessels functionalised with VEGF are coated with a layer of endothelial cells after in vivo implantation, but the source of the cells are unknown. Here the authors provide evidence that monocytes expressing VEGF receptors can transdifferentiate into endothelial cells via...

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Autores principales:	Randall J. Smith, Bita Nasiri, Julien Kann, Donald Yergeau, Jonathan E. Bard, Daniel D. Swartz, Stelios T. Andreadis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/87d73685b94348bba1f801f3cacbabba
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spelling	oai:doaj.org-article:87d73685b94348bba1f801f3cacbabba2021-12-02T16:49:30ZEndothelialization of arterial vascular grafts by circulating monocytes10.1038/s41467-020-15361-22041-1723https://doaj.org/article/87d73685b94348bba1f801f3cacbabba2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15361-2https://doaj.org/toc/2041-1723Acellular tissue engineered vessels functionalised with VEGF are coated with a layer of endothelial cells after in vivo implantation, but the source of the cells are unknown. Here the authors provide evidence that monocytes expressing VEGF receptors can transdifferentiate into endothelial cells via a macrophage intermediate.Randall J. SmithBita NasiriJulien KannDonald YergeauJonathan E. BardDaniel D. SwartzStelios T. AndreadisNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Randall J. Smith Bita Nasiri Julien Kann Donald Yergeau Jonathan E. Bard Daniel D. Swartz Stelios T. Andreadis Endothelialization of arterial vascular grafts by circulating monocytes
description	Acellular tissue engineered vessels functionalised with VEGF are coated with a layer of endothelial cells after in vivo implantation, but the source of the cells are unknown. Here the authors provide evidence that monocytes expressing VEGF receptors can transdifferentiate into endothelial cells via a macrophage intermediate.
format	article
author	Randall J. Smith Bita Nasiri Julien Kann Donald Yergeau Jonathan E. Bard Daniel D. Swartz Stelios T. Andreadis
author_facet	Randall J. Smith Bita Nasiri Julien Kann Donald Yergeau Jonathan E. Bard Daniel D. Swartz Stelios T. Andreadis
author_sort	Randall J. Smith
title	Endothelialization of arterial vascular grafts by circulating monocytes
title_short	Endothelialization of arterial vascular grafts by circulating monocytes
title_full	Endothelialization of arterial vascular grafts by circulating monocytes
title_fullStr	Endothelialization of arterial vascular grafts by circulating monocytes
title_full_unstemmed	Endothelialization of arterial vascular grafts by circulating monocytes
title_sort	endothelialization of arterial vascular grafts by circulating monocytes
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/87d73685b94348bba1f801f3cacbabba
work_keys_str_mv	AT randalljsmith endothelializationofarterialvasculargraftsbycirculatingmonocytes AT bitanasiri endothelializationofarterialvasculargraftsbycirculatingmonocytes AT julienkann endothelializationofarterialvasculargraftsbycirculatingmonocytes AT donaldyergeau endothelializationofarterialvasculargraftsbycirculatingmonocytes AT jonathanebard endothelializationofarterialvasculargraftsbycirculatingmonocytes AT danieldswartz endothelializationofarterialvasculargraftsbycirculatingmonocytes AT steliostandreadis endothelializationofarterialvasculargraftsbycirculatingmonocytes
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Endothelialization of arterial vascular grafts by circulating monocytes

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