Effects of 1.5 and 4.3 GHz microwave radiation on cognitive function and hippocampal tissue structure in Wistar rats

Abstract Previous studies have shown that single-frequency microwave radiation can lead to cognitive decline in rats. However, few studies have focused on the combined effects of irradiation with different frequencies of microwaves. Our research aimed to investigate the effects of 1.5 GHz and 4.3 GH...

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Autores principales:	Ruiqing Zhu, Hui Wang, Xinping Xu, Li Zhao, Jing Zhang, Ji Dong, Binwei Yao, Haoyu Wang, Hongmei Zhou, Yabing Gao, Ruiyun Peng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/87e26c7f5cb243608b3bf2a7ecb7f61d
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spelling	oai:doaj.org-article:87e26c7f5cb243608b3bf2a7ecb7f61d2021-12-02T17:15:24ZEffects of 1.5 and 4.3 GHz microwave radiation on cognitive function and hippocampal tissue structure in Wistar rats10.1038/s41598-021-89348-42045-2322https://doaj.org/article/87e26c7f5cb243608b3bf2a7ecb7f61d2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-89348-4https://doaj.org/toc/2045-2322Abstract Previous studies have shown that single-frequency microwave radiation can lead to cognitive decline in rats. However, few studies have focused on the combined effects of irradiation with different frequencies of microwaves. Our research aimed to investigate the effects of 1.5 GHz and 4.3 GHz microwave radiation, singly and in combination, on cognitive function and hippocampal tissue structure in rats. A total of 140 male Wistar rats were randomly divided into 4 groups: the S group (sham radiation group), L10 group (10 mW/cm2 1.5 GHz group), C10 group (10 mW/cm2 4.3 GHz band group) and LC10 group (10 mW/cm2 1.5 and 4.3 GHz multi-frequency radiation group). For 1–28 days after microwave radiation, we analyzed the average escape latency for the Morris water maze task, electroencephalograms, change in hippocampal tissue structure and ultrastructure, content of the Nissl body in the hippocampus, and activities of lactate dehydrogenase and succinate dehydrogenase. Compared to the S group, all exposure groups showed varying degrees of learning and memory decline and hippocampal structural damage. The results showed that 1.5 GHz and 4.3 GHz microwave radiation was able to induce cognitive impairment and hippocampal tissue damage in rats and combined radiation with both frequencies caused more serious injuries, but none of these damaging effects varied with microwave frequency.Ruiqing ZhuHui WangXinping XuLi ZhaoJing ZhangJi DongBinwei YaoHaoyu WangHongmei ZhouYabing GaoRuiyun PengNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ruiqing Zhu Hui Wang Xinping Xu Li Zhao Jing Zhang Ji Dong Binwei Yao Haoyu Wang Hongmei Zhou Yabing Gao Ruiyun Peng Effects of 1.5 and 4.3 GHz microwave radiation on cognitive function and hippocampal tissue structure in Wistar rats
description	Abstract Previous studies have shown that single-frequency microwave radiation can lead to cognitive decline in rats. However, few studies have focused on the combined effects of irradiation with different frequencies of microwaves. Our research aimed to investigate the effects of 1.5 GHz and 4.3 GHz microwave radiation, singly and in combination, on cognitive function and hippocampal tissue structure in rats. A total of 140 male Wistar rats were randomly divided into 4 groups: the S group (sham radiation group), L10 group (10 mW/cm2 1.5 GHz group), C10 group (10 mW/cm2 4.3 GHz band group) and LC10 group (10 mW/cm2 1.5 and 4.3 GHz multi-frequency radiation group). For 1–28 days after microwave radiation, we analyzed the average escape latency for the Morris water maze task, electroencephalograms, change in hippocampal tissue structure and ultrastructure, content of the Nissl body in the hippocampus, and activities of lactate dehydrogenase and succinate dehydrogenase. Compared to the S group, all exposure groups showed varying degrees of learning and memory decline and hippocampal structural damage. The results showed that 1.5 GHz and 4.3 GHz microwave radiation was able to induce cognitive impairment and hippocampal tissue damage in rats and combined radiation with both frequencies caused more serious injuries, but none of these damaging effects varied with microwave frequency.
format	article
author	Ruiqing Zhu Hui Wang Xinping Xu Li Zhao Jing Zhang Ji Dong Binwei Yao Haoyu Wang Hongmei Zhou Yabing Gao Ruiyun Peng
author_facet	Ruiqing Zhu Hui Wang Xinping Xu Li Zhao Jing Zhang Ji Dong Binwei Yao Haoyu Wang Hongmei Zhou Yabing Gao Ruiyun Peng
author_sort	Ruiqing Zhu
title	Effects of 1.5 and 4.3 GHz microwave radiation on cognitive function and hippocampal tissue structure in Wistar rats
title_short	Effects of 1.5 and 4.3 GHz microwave radiation on cognitive function and hippocampal tissue structure in Wistar rats
title_full	Effects of 1.5 and 4.3 GHz microwave radiation on cognitive function and hippocampal tissue structure in Wistar rats
title_fullStr	Effects of 1.5 and 4.3 GHz microwave radiation on cognitive function and hippocampal tissue structure in Wistar rats
title_full_unstemmed	Effects of 1.5 and 4.3 GHz microwave radiation on cognitive function and hippocampal tissue structure in Wistar rats
title_sort	effects of 1.5 and 4.3 ghz microwave radiation on cognitive function and hippocampal tissue structure in wistar rats
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/87e26c7f5cb243608b3bf2a7ecb7f61d
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Effects of 1.5 and 4.3 GHz microwave radiation on cognitive function and hippocampal tissue structure in Wistar rats

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