Flexible genes establish widespread bacteriophage pan-genomes in cryoconite hole ecosystems

Bacteriophages and their hosts are involved in a constant evolutionary arms race that should lead to divergence between phage genes over time. Here, the authors recruit metagenomic reads to virus reference genomes and genome fragments in samples from cryoconite holes and show that phages with near-i...

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Auteurs principaux:	Christopher M. Bellas, Declan C. Schroeder, Arwyn Edwards, Gary Barker, Alexandre M. Anesio
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2020
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/87e483e9dc33413790e4656412d76b4c
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spelling	oai:doaj.org-article:87e483e9dc33413790e4656412d76b4c2021-12-02T15:25:36ZFlexible genes establish widespread bacteriophage pan-genomes in cryoconite hole ecosystems10.1038/s41467-020-18236-82041-1723https://doaj.org/article/87e483e9dc33413790e4656412d76b4c2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18236-8https://doaj.org/toc/2041-1723Bacteriophages and their hosts are involved in a constant evolutionary arms race that should lead to divergence between phage genes over time. Here, the authors recruit metagenomic reads to virus reference genomes and genome fragments in samples from cryoconite holes and show that phages with near-identical core genomes maintain diversity by possession of numerous flexible gene modules, where homologous genes present in the pan-genome interchange to create new phage variants.Christopher M. BellasDeclan C. SchroederArwyn EdwardsGary BarkerAlexandre M. AnesioNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Christopher M. Bellas Declan C. Schroeder Arwyn Edwards Gary Barker Alexandre M. Anesio Flexible genes establish widespread bacteriophage pan-genomes in cryoconite hole ecosystems
description	Bacteriophages and their hosts are involved in a constant evolutionary arms race that should lead to divergence between phage genes over time. Here, the authors recruit metagenomic reads to virus reference genomes and genome fragments in samples from cryoconite holes and show that phages with near-identical core genomes maintain diversity by possession of numerous flexible gene modules, where homologous genes present in the pan-genome interchange to create new phage variants.
format	article
author	Christopher M. Bellas Declan C. Schroeder Arwyn Edwards Gary Barker Alexandre M. Anesio
author_facet	Christopher M. Bellas Declan C. Schroeder Arwyn Edwards Gary Barker Alexandre M. Anesio
author_sort	Christopher M. Bellas
title	Flexible genes establish widespread bacteriophage pan-genomes in cryoconite hole ecosystems
title_short	Flexible genes establish widespread bacteriophage pan-genomes in cryoconite hole ecosystems
title_full	Flexible genes establish widespread bacteriophage pan-genomes in cryoconite hole ecosystems
title_fullStr	Flexible genes establish widespread bacteriophage pan-genomes in cryoconite hole ecosystems
title_full_unstemmed	Flexible genes establish widespread bacteriophage pan-genomes in cryoconite hole ecosystems
title_sort	flexible genes establish widespread bacteriophage pan-genomes in cryoconite hole ecosystems
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/87e483e9dc33413790e4656412d76b4c
work_keys_str_mv	AT christophermbellas flexiblegenesestablishwidespreadbacteriophagepangenomesincryoconiteholeecosystems AT declancschroeder flexiblegenesestablishwidespreadbacteriophagepangenomesincryoconiteholeecosystems AT arwynedwards flexiblegenesestablishwidespreadbacteriophagepangenomesincryoconiteholeecosystems AT garybarker flexiblegenesestablishwidespreadbacteriophagepangenomesincryoconiteholeecosystems AT alexandremanesio flexiblegenesestablishwidespreadbacteriophagepangenomesincryoconiteholeecosystems
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Flexible genes establish widespread bacteriophage pan-genomes in cryoconite hole ecosystems

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