Glycemic control and diabetes complications among diabetes mellitus patients attending at University of Gondar Hospital, Northwest Ethiopia

Alebachew Fasil, Belete Biadgo, Molla Abebe Department of Clinical Chemistry, College of Medicine and Health Sciences, School of Biomedical and Laboratory Sciences, University of Gondar, Gondar, Ethiopia Background: Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemi...

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Autores principales:	Fasil A, Biadgo B, Abebe M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Diabetes Mellitus; Glycemic control Diabetes complications Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/87eb0c7d1952412e9053754019e7c1a2
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spelling	oai:doaj.org-article:87eb0c7d1952412e9053754019e7c1a22021-12-02T06:27:51ZGlycemic control and diabetes complications among diabetes mellitus patients attending at University of Gondar Hospital, Northwest Ethiopia1178-7007https://doaj.org/article/87eb0c7d1952412e9053754019e7c1a22018-12-01T00:00:00Zhttps://www.dovepress.com/glycemic-control-and-diabetes-complications-among-diabetes-mellitus-pa-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Alebachew Fasil, Belete Biadgo, Molla Abebe Department of Clinical Chemistry, College of Medicine and Health Sciences, School of Biomedical and Laboratory Sciences, University of Gondar, Gondar, Ethiopia Background: Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia due to either insulin deficiency or resistance or both. Hyperglycemia induces tissue damage through mitochondrial superoxide production, affecting retina, glomerulus, and neurons. It requires continuing medical care and ongoing self-care management to prevent and delay acute and long-term complications. Therefore, our study was designed to assess glycemic control and diabetes complications among diabetes patients attending at University of Gondar Hospital.Materials and methods: A cross-sectional study was conducted among DM patients attending at University of Gondar Hospital diabetes follow-up clinic during February–March 2017. Five milliliters of blood was collected using aseptic technique. Levels of fasting blood sugar (FBS), triglycerides, and cholesterol were measured using MINDRAY BS-200E machine. FBS ≥152 mg/dL was taken as poor glycemic control. Binary and multivariable logistic regression models were used to evaluate associated risk factors for the outcome variable. A P-value of <0.05 was considered as statistically significant.Result: Three hundred sixty-seven diabetes patients were included in this study. About 222 (60.5%) of them had poor glycemic control (FBS ≥152 mg/dL). The proportion of poor glycemic control was slightly higher among type 1 DM patients (61.4%) than type 2 DM patients (59.8%). Age ≥65 years (adjusted odds ratio [AOR]: 0.070; 95% CI: 0.016–0.308), being divorced (AOR: 0.226; 95% CI: 0.064–0.8000), and increased waist circumference (AOR: 0.361: 95% CI: 0.181–0.720) were factors that significantly reduce poor glycemic control. Diabetes complications were slightly higher in insulin- and tablet-only users, 72.5% and 64.5%, respectively. DM complications were also higher in patients who had poor glycemic control (61/222) and type 2 diabetes (78 [37.3%]).Conclusion: Prevalence of poor glycemic control and DM complications was high, which indicate that appropriate intervention is required to improve glycemic control and prevent or control complications among DM patients. Keywords: diabetes mellitus, glycemic control, diabetes complications, EthiopiaFasil ABiadgo BAbebe MDove Medical PressarticleDiabetes Mellitus; Glycemic controlDiabetes complicationsSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 12, Pp 75-83 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diabetes Mellitus; Glycemic control Diabetes complications Specialties of internal medicine RC581-951
spellingShingle	Diabetes Mellitus; Glycemic control Diabetes complications Specialties of internal medicine RC581-951 Fasil A Biadgo B Abebe M Glycemic control and diabetes complications among diabetes mellitus patients attending at University of Gondar Hospital, Northwest Ethiopia
description	Alebachew Fasil, Belete Biadgo, Molla Abebe Department of Clinical Chemistry, College of Medicine and Health Sciences, School of Biomedical and Laboratory Sciences, University of Gondar, Gondar, Ethiopia Background: Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia due to either insulin deficiency or resistance or both. Hyperglycemia induces tissue damage through mitochondrial superoxide production, affecting retina, glomerulus, and neurons. It requires continuing medical care and ongoing self-care management to prevent and delay acute and long-term complications. Therefore, our study was designed to assess glycemic control and diabetes complications among diabetes patients attending at University of Gondar Hospital.Materials and methods: A cross-sectional study was conducted among DM patients attending at University of Gondar Hospital diabetes follow-up clinic during February–March 2017. Five milliliters of blood was collected using aseptic technique. Levels of fasting blood sugar (FBS), triglycerides, and cholesterol were measured using MINDRAY BS-200E machine. FBS ≥152 mg/dL was taken as poor glycemic control. Binary and multivariable logistic regression models were used to evaluate associated risk factors for the outcome variable. A P-value of <0.05 was considered as statistically significant.Result: Three hundred sixty-seven diabetes patients were included in this study. About 222 (60.5%) of them had poor glycemic control (FBS ≥152 mg/dL). The proportion of poor glycemic control was slightly higher among type 1 DM patients (61.4%) than type 2 DM patients (59.8%). Age ≥65 years (adjusted odds ratio [AOR]: 0.070; 95% CI: 0.016–0.308), being divorced (AOR: 0.226; 95% CI: 0.064–0.8000), and increased waist circumference (AOR: 0.361: 95% CI: 0.181–0.720) were factors that significantly reduce poor glycemic control. Diabetes complications were slightly higher in insulin- and tablet-only users, 72.5% and 64.5%, respectively. DM complications were also higher in patients who had poor glycemic control (61/222) and type 2 diabetes (78 [37.3%]).Conclusion: Prevalence of poor glycemic control and DM complications was high, which indicate that appropriate intervention is required to improve glycemic control and prevent or control complications among DM patients. Keywords: diabetes mellitus, glycemic control, diabetes complications, Ethiopia
format	article
author	Fasil A Biadgo B Abebe M
author_facet	Fasil A Biadgo B Abebe M
author_sort	Fasil A
title	Glycemic control and diabetes complications among diabetes mellitus patients attending at University of Gondar Hospital, Northwest Ethiopia
title_short	Glycemic control and diabetes complications among diabetes mellitus patients attending at University of Gondar Hospital, Northwest Ethiopia
title_full	Glycemic control and diabetes complications among diabetes mellitus patients attending at University of Gondar Hospital, Northwest Ethiopia
title_fullStr	Glycemic control and diabetes complications among diabetes mellitus patients attending at University of Gondar Hospital, Northwest Ethiopia
title_full_unstemmed	Glycemic control and diabetes complications among diabetes mellitus patients attending at University of Gondar Hospital, Northwest Ethiopia
title_sort	glycemic control and diabetes complications among diabetes mellitus patients attending at university of gondar hospital, northwest ethiopia
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/87eb0c7d1952412e9053754019e7c1a2
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Glycemic control and diabetes complications among diabetes mellitus patients attending at University of Gondar Hospital, Northwest Ethiopia

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