Replication confers β cell immaturity

Adult beta cells, which are highly specialised insulin-secreting cells, rarely replicate. Puri et al. demonstrate that beta cell proliferative capacity is inversely correlated with their functionality and differentiation state, by inducing proliferation of adult cells with ectopic overexpression of...

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Autores principales: Sapna Puri, Nilotpal Roy, Holger A. Russ, Laura Leonhardt, Esra K. French, Ritu Roy, Henrik Bengtsson, Donald K. Scott, Andrew F. Stewart, Matthias Hebrok
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/87ec84a80d19444a9d09ade990a1127e
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