The effect of bioadhesive in reduction of pain and healing time of Aphtha

Background and Objective: On the basis of etiology of aphthous ulcer, there are many factors, which cause this problem such as immunologic and hematologic disorders and emotional stress. For treating this disorder, it is recommended using a steroid drug. This study was performed to investigate one o...

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Autores principales:	M Motaleb Nejad, AA Moghadam Nia, E Mohammadi
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2003
Materias:	oral aphthous ulcer bioadhesive corticosteroid triamcinolone acetonide minor aphthous ulcer Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/8807135270c647efb04a3d6bf7684066
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spelling	oai:doaj.org-article:8807135270c647efb04a3d6bf76840662021-11-10T09:18:00ZThe effect of bioadhesive in reduction of pain and healing time of Aphtha1561-41072251-7170https://doaj.org/article/8807135270c647efb04a3d6bf76840662003-01-01T00:00:00Zhttp://jbums.org/article-1-2794-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and Objective: On the basis of etiology of aphthous ulcer, there are many factors, which cause this problem such as immunologic and hematologic disorders and emotional stress. For treating this disorder, it is recommended using a steroid drug. This study was performed to investigate one of the natural bases as a bioadhesive dosage form in the management of aphthous ulcer. Methods: In this experimental study, there were two groups. The first twenty persons received bioadhesive without triamcinolone acetonide (As pilot study) for determining the rate of adherence and possibly side effects of the bioadhesive. The second twenty persons as case and control, with history of minor aphthous ulcer were selected and treated in two courses of disease, once with bioadhesive containing drug (Case) and once again without drug (Control). The data were statistically analyzed by using student t-test. Findings: In the pilot study group, duration of adherence on the oral cavity was more than 20 minutes and there were not side effects or undesirable reactions such as bad smell or taste. There was not significant difference in analgesia and healing time course between case and control groups. Healing time in case and control groups after treatment were shorter than before treatment (P<0.000). Conclusion: Using bioadhesive as coating and protective agent may cause reduction of pain and healing time course. Also, triamcinolone in bioadhesive don’t affect on reduction of pain and healing time.M Motaleb NejadAA Moghadam NiaE MohammadiBabol University of Medical Sciencesarticleoral aphthous ulcerbioadhesivecorticosteroidtriamcinolone acetonideminor aphthous ulcerMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 5, Iss 1, Pp 12-16 (2003)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	oral aphthous ulcer bioadhesive corticosteroid triamcinolone acetonide minor aphthous ulcer Medicine R Medicine (General) R5-920
spellingShingle	oral aphthous ulcer bioadhesive corticosteroid triamcinolone acetonide minor aphthous ulcer Medicine R Medicine (General) R5-920 M Motaleb Nejad AA Moghadam Nia E Mohammadi The effect of bioadhesive in reduction of pain and healing time of Aphtha
description	Background and Objective: On the basis of etiology of aphthous ulcer, there are many factors, which cause this problem such as immunologic and hematologic disorders and emotional stress. For treating this disorder, it is recommended using a steroid drug. This study was performed to investigate one of the natural bases as a bioadhesive dosage form in the management of aphthous ulcer. Methods: In this experimental study, there were two groups. The first twenty persons received bioadhesive without triamcinolone acetonide (As pilot study) for determining the rate of adherence and possibly side effects of the bioadhesive. The second twenty persons as case and control, with history of minor aphthous ulcer were selected and treated in two courses of disease, once with bioadhesive containing drug (Case) and once again without drug (Control). The data were statistically analyzed by using student t-test. Findings: In the pilot study group, duration of adherence on the oral cavity was more than 20 minutes and there were not side effects or undesirable reactions such as bad smell or taste. There was not significant difference in analgesia and healing time course between case and control groups. Healing time in case and control groups after treatment were shorter than before treatment (P<0.000). Conclusion: Using bioadhesive as coating and protective agent may cause reduction of pain and healing time course. Also, triamcinolone in bioadhesive don’t affect on reduction of pain and healing time.
format	article
author	M Motaleb Nejad AA Moghadam Nia E Mohammadi
author_facet	M Motaleb Nejad AA Moghadam Nia E Mohammadi
author_sort	M Motaleb Nejad
title	The effect of bioadhesive in reduction of pain and healing time of Aphtha
title_short	The effect of bioadhesive in reduction of pain and healing time of Aphtha
title_full	The effect of bioadhesive in reduction of pain and healing time of Aphtha
title_fullStr	The effect of bioadhesive in reduction of pain and healing time of Aphtha
title_full_unstemmed	The effect of bioadhesive in reduction of pain and healing time of Aphtha
title_sort	effect of bioadhesive in reduction of pain and healing time of aphtha
publisher	Babol University of Medical Sciences
publishDate	2003
url	https://doaj.org/article/8807135270c647efb04a3d6bf7684066
work_keys_str_mv	AT mmotalebnejad theeffectofbioadhesiveinreductionofpainandhealingtimeofaphtha AT aamoghadamnia theeffectofbioadhesiveinreductionofpainandhealingtimeofaphtha AT emohammadi theeffectofbioadhesiveinreductionofpainandhealingtimeofaphtha AT mmotalebnejad effectofbioadhesiveinreductionofpainandhealingtimeofaphtha AT aamoghadamnia effectofbioadhesiveinreductionofpainandhealingtimeofaphtha AT emohammadi effectofbioadhesiveinreductionofpainandhealingtimeofaphtha
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The effect of bioadhesive in reduction of pain and healing time of Aphtha

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