High-throughput discovery of organic cages and catenanes using computational screening fused with robotic synthesis

Supramolecular assemblies remain of great importance to a variety of fields, yet their targeted design and synthesis remains highly challenging. Here, Cooper and colleagues combine computational screening with high-throughput robotic synthesis and discover 33 new organic cage molecules that form cle...

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Autores principales:	R. L. Greenaway, V. Santolini, M. J. Bennison, B. M. Alston, C. J. Pugh, M. A. Little, M. Miklitz, E. G. B. Eden-Rump, R. Clowes, A. Shakil, H. J. Cuthbertson, H. Armstrong, M. E. Briggs, K. E. Jelfs, A. I. Cooper
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/88188673cb8a4e62a1f6457b189cfa96
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spelling	oai:doaj.org-article:88188673cb8a4e62a1f6457b189cfa962021-12-02T16:56:42ZHigh-throughput discovery of organic cages and catenanes using computational screening fused with robotic synthesis10.1038/s41467-018-05271-92041-1723https://doaj.org/article/88188673cb8a4e62a1f6457b189cfa962018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05271-9https://doaj.org/toc/2041-1723Supramolecular assemblies remain of great importance to a variety of fields, yet their targeted design and synthesis remains highly challenging. Here, Cooper and colleagues combine computational screening with high-throughput robotic synthesis and discover 33 new organic cage molecules that form cleanly in one-pot syntheses.R. L. GreenawayV. SantoliniM. J. BennisonB. M. AlstonC. J. PughM. A. LittleM. MiklitzE. G. B. Eden-RumpR. ClowesA. ShakilH. J. CuthbertsonH. ArmstrongM. E. BriggsK. E. JelfsA. I. CooperNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q R. L. Greenaway V. Santolini M. J. Bennison B. M. Alston C. J. Pugh M. A. Little M. Miklitz E. G. B. Eden-Rump R. Clowes A. Shakil H. J. Cuthbertson H. Armstrong M. E. Briggs K. E. Jelfs A. I. Cooper High-throughput discovery of organic cages and catenanes using computational screening fused with robotic synthesis
description	Supramolecular assemblies remain of great importance to a variety of fields, yet their targeted design and synthesis remains highly challenging. Here, Cooper and colleagues combine computational screening with high-throughput robotic synthesis and discover 33 new organic cage molecules that form cleanly in one-pot syntheses.
format	article
author	R. L. Greenaway V. Santolini M. J. Bennison B. M. Alston C. J. Pugh M. A. Little M. Miklitz E. G. B. Eden-Rump R. Clowes A. Shakil H. J. Cuthbertson H. Armstrong M. E. Briggs K. E. Jelfs A. I. Cooper
author_facet	R. L. Greenaway V. Santolini M. J. Bennison B. M. Alston C. J. Pugh M. A. Little M. Miklitz E. G. B. Eden-Rump R. Clowes A. Shakil H. J. Cuthbertson H. Armstrong M. E. Briggs K. E. Jelfs A. I. Cooper
author_sort	R. L. Greenaway
title	High-throughput discovery of organic cages and catenanes using computational screening fused with robotic synthesis
title_short	High-throughput discovery of organic cages and catenanes using computational screening fused with robotic synthesis
title_full	High-throughput discovery of organic cages and catenanes using computational screening fused with robotic synthesis
title_fullStr	High-throughput discovery of organic cages and catenanes using computational screening fused with robotic synthesis
title_full_unstemmed	High-throughput discovery of organic cages and catenanes using computational screening fused with robotic synthesis
title_sort	high-throughput discovery of organic cages and catenanes using computational screening fused with robotic synthesis
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/88188673cb8a4e62a1f6457b189cfa96
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High-throughput discovery of organic cages and catenanes using computational screening fused with robotic synthesis

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