Crosstalk and the evolvability of intracellular communication

The evolutionary rationale behind the extensive crosstalk between Metazoan signalling pathways remains elusive. Here the authors provide evidence that crosstalk in the human signalling network evolves as a means to allow efficient diversification of cellular responses to the same signals between dif...

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Detalles Bibliográficos
Autores principales:	Michael A. Rowland, Joseph M. Greenbaum, Eric J. Deeds
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8825234ddb054784a849faea7e1a4bb6
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spelling	oai:doaj.org-article:8825234ddb054784a849faea7e1a4bb62021-12-02T14:40:33ZCrosstalk and the evolvability of intracellular communication10.1038/ncomms160092041-1723https://doaj.org/article/8825234ddb054784a849faea7e1a4bb62017-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms16009https://doaj.org/toc/2041-1723The evolutionary rationale behind the extensive crosstalk between Metazoan signalling pathways remains elusive. Here the authors provide evidence that crosstalk in the human signalling network evolves as a means to allow efficient diversification of cellular responses to the same signals between different cell types.Michael A. RowlandJoseph M. GreenbaumEric J. DeedsNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Michael A. Rowland Joseph M. Greenbaum Eric J. Deeds Crosstalk and the evolvability of intracellular communication
description	The evolutionary rationale behind the extensive crosstalk between Metazoan signalling pathways remains elusive. Here the authors provide evidence that crosstalk in the human signalling network evolves as a means to allow efficient diversification of cellular responses to the same signals between different cell types.
format	article
author	Michael A. Rowland Joseph M. Greenbaum Eric J. Deeds
author_facet	Michael A. Rowland Joseph M. Greenbaum Eric J. Deeds
author_sort	Michael A. Rowland
title	Crosstalk and the evolvability of intracellular communication
title_short	Crosstalk and the evolvability of intracellular communication
title_full	Crosstalk and the evolvability of intracellular communication
title_fullStr	Crosstalk and the evolvability of intracellular communication
title_full_unstemmed	Crosstalk and the evolvability of intracellular communication
title_sort	crosstalk and the evolvability of intracellular communication
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/8825234ddb054784a849faea7e1a4bb6
work_keys_str_mv	AT michaelarowland crosstalkandtheevolvabilityofintracellularcommunication AT josephmgreenbaum crosstalkandtheevolvabilityofintracellularcommunication AT ericjdeeds crosstalkandtheevolvabilityofintracellularcommunication
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Crosstalk and the evolvability of intracellular communication

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