Nanoscopic subcellular imaging enabled by ion beam tomography

Secondary ion beam mass spectrometry (SIMS) is a method to obtain a chemical snapshot of biological tissue, but the spatial resolution is low. Here, the authors develop a computational and technology pipeline to localise a chemical signal in SIMS in 3D and sub-25 nm accuracy, called Ion Beam Tomogra...

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Autores principales:	Ahmet F. Coskun, Guojun Han, Shambavi Ganesh, Shih-Yu Chen, Xavier Rovira Clavé, Stefan Harmsen, Sizun Jiang, Christian M. Schürch, Yunhao Bai, Chuck Hitzman, Garry P. Nolan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/882ce2bc30f347449f3e0769771cb2d7
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spelling	oai:doaj.org-article:882ce2bc30f347449f3e0769771cb2d72021-12-02T14:06:22ZNanoscopic subcellular imaging enabled by ion beam tomography10.1038/s41467-020-20753-52041-1723https://doaj.org/article/882ce2bc30f347449f3e0769771cb2d72021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20753-5https://doaj.org/toc/2041-1723Secondary ion beam mass spectrometry (SIMS) is a method to obtain a chemical snapshot of biological tissue, but the spatial resolution is low. Here, the authors develop a computational and technology pipeline to localise a chemical signal in SIMS in 3D and sub-25 nm accuracy, called Ion Beam TomographyAhmet F. CoskunGuojun HanShambavi GaneshShih-Yu ChenXavier Rovira ClavéStefan HarmsenSizun JiangChristian M. SchürchYunhao BaiChuck HitzmanGarry P. NolanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ahmet F. Coskun Guojun Han Shambavi Ganesh Shih-Yu Chen Xavier Rovira Clavé Stefan Harmsen Sizun Jiang Christian M. Schürch Yunhao Bai Chuck Hitzman Garry P. Nolan Nanoscopic subcellular imaging enabled by ion beam tomography
description	Secondary ion beam mass spectrometry (SIMS) is a method to obtain a chemical snapshot of biological tissue, but the spatial resolution is low. Here, the authors develop a computational and technology pipeline to localise a chemical signal in SIMS in 3D and sub-25 nm accuracy, called Ion Beam Tomography
format	article
author	Ahmet F. Coskun Guojun Han Shambavi Ganesh Shih-Yu Chen Xavier Rovira Clavé Stefan Harmsen Sizun Jiang Christian M. Schürch Yunhao Bai Chuck Hitzman Garry P. Nolan
author_facet	Ahmet F. Coskun Guojun Han Shambavi Ganesh Shih-Yu Chen Xavier Rovira Clavé Stefan Harmsen Sizun Jiang Christian M. Schürch Yunhao Bai Chuck Hitzman Garry P. Nolan
author_sort	Ahmet F. Coskun
title	Nanoscopic subcellular imaging enabled by ion beam tomography
title_short	Nanoscopic subcellular imaging enabled by ion beam tomography
title_full	Nanoscopic subcellular imaging enabled by ion beam tomography
title_fullStr	Nanoscopic subcellular imaging enabled by ion beam tomography
title_full_unstemmed	Nanoscopic subcellular imaging enabled by ion beam tomography
title_sort	nanoscopic subcellular imaging enabled by ion beam tomography
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/882ce2bc30f347449f3e0769771cb2d7
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Nanoscopic subcellular imaging enabled by ion beam tomography

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