Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor.

<h4>Background</h4>Dot1L, a histone methyltransferase that targets histone H3 lysine 79 (H3K79), has been implicated in gene regulation and the DNA damage response although its functions in these processes remain poorly defined.<h4>Methodology/principal findings</h4>Using the...

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Autores principales: Jennifer FitzGerald, Sylvie Moureau, Paul Drogaris, Enda O'Connell, Nebiyu Abshiru, Alain Verreault, Pierre Thibault, Muriel Grenon, Noel F Lowndes
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/88377b771a5243508fc14e3367b752f9
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