PTENβ is an alternatively translated isoform of PTEN that regulates rDNA transcription

PTEN is a potent tumour suppressor involved in cell growth, proliferation and survival. Here the authors identify an N-terminal extended isoform of PTEN, termed PTENβ that negatively regulates ribosomal DNA transcription and cell proliferation, expanding the pleiotropic functions of the PTEN family....

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Autores principales:	Hui Liang, Xi Chen, Qi Yin, Danhui Ruan, Xuyang Zhao, Cong Zhang, Michael A. McNutt, Yuxin Yin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/883da98b6f924e5d8e3d415cd77b2dab
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spelling	oai:doaj.org-article:883da98b6f924e5d8e3d415cd77b2dab2021-12-02T17:06:03ZPTENβ is an alternatively translated isoform of PTEN that regulates rDNA transcription10.1038/ncomms147712041-1723https://doaj.org/article/883da98b6f924e5d8e3d415cd77b2dab2017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14771https://doaj.org/toc/2041-1723PTEN is a potent tumour suppressor involved in cell growth, proliferation and survival. Here the authors identify an N-terminal extended isoform of PTEN, termed PTENβ that negatively regulates ribosomal DNA transcription and cell proliferation, expanding the pleiotropic functions of the PTEN family.Hui LiangXi ChenQi YinDanhui RuanXuyang ZhaoCong ZhangMichael A. McNuttYuxin YinNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hui Liang Xi Chen Qi Yin Danhui Ruan Xuyang Zhao Cong Zhang Michael A. McNutt Yuxin Yin PTENβ is an alternatively translated isoform of PTEN that regulates rDNA transcription
description	PTEN is a potent tumour suppressor involved in cell growth, proliferation and survival. Here the authors identify an N-terminal extended isoform of PTEN, termed PTENβ that negatively regulates ribosomal DNA transcription and cell proliferation, expanding the pleiotropic functions of the PTEN family.
format	article
author	Hui Liang Xi Chen Qi Yin Danhui Ruan Xuyang Zhao Cong Zhang Michael A. McNutt Yuxin Yin
author_facet	Hui Liang Xi Chen Qi Yin Danhui Ruan Xuyang Zhao Cong Zhang Michael A. McNutt Yuxin Yin
author_sort	Hui Liang
title	PTENβ is an alternatively translated isoform of PTEN that regulates rDNA transcription
title_short	PTENβ is an alternatively translated isoform of PTEN that regulates rDNA transcription
title_full	PTENβ is an alternatively translated isoform of PTEN that regulates rDNA transcription
title_fullStr	PTENβ is an alternatively translated isoform of PTEN that regulates rDNA transcription
title_full_unstemmed	PTENβ is an alternatively translated isoform of PTEN that regulates rDNA transcription
title_sort	ptenβ is an alternatively translated isoform of pten that regulates rdna transcription
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/883da98b6f924e5d8e3d415cd77b2dab
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PTENβ is an alternatively translated isoform of PTEN that regulates rDNA transcription

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