Deficiency of ASGR1 in pigs recapitulates reduced risk factor for cardiovascular disease in humans
Genetic variants in the asialoglycoprotein receptor 1 (ASGR1) are associated with a reduced risk of cardiovascular disease (CVD) in humans. However, the underlying molecular mechanism remains elusive. Given the cardiovascular similarities between pigs and humans, we generated ASGR1-deficient pigs us...
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| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
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Public Library of Science (PLoS)
2021
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| Acceso en línea: | https://doaj.org/article/8844bd7497d64e73ab87e18292a072e0 |
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por Baocai Xie, Xiaochen Shi, Yan Li, Bo Xia, Jia Zhou, Minjie Du, Xiangyang Xing, Liang Bai, Enqi Liu, Fernando Alvarez, Long Jin, Shaoping Deng, Grant A Mitchell, Dengke Pan, Mingzhou Li, Jiangwei Wu
Publicado 2021
Enlace del recursoPublicado 2021
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