Inequality in genetic cancer risk suggests bad genes rather than bad luck

Cancer heritability estimates can be obtained via decomposing trait variance into genetic and other factors. Here, the authors obtain the distribution of absolute genetic risk for 15 common cancers, and they use a number of metrics to show that the genetic risk varies considerably across individuals...

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Autores principales:	Mats Julius Stensrud, Morten Valberg
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/884a5552326249eeaac05b90fac62174
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spelling	oai:doaj.org-article:884a5552326249eeaac05b90fac621742021-12-02T14:40:35ZInequality in genetic cancer risk suggests bad genes rather than bad luck10.1038/s41467-017-01284-y2041-1723https://doaj.org/article/884a5552326249eeaac05b90fac621742017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01284-yhttps://doaj.org/toc/2041-1723Cancer heritability estimates can be obtained via decomposing trait variance into genetic and other factors. Here, the authors obtain the distribution of absolute genetic risk for 15 common cancers, and they use a number of metrics to show that the genetic risk varies considerably across individuals.Mats Julius StensrudMorten ValbergNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mats Julius Stensrud Morten Valberg Inequality in genetic cancer risk suggests bad genes rather than bad luck
description	Cancer heritability estimates can be obtained via decomposing trait variance into genetic and other factors. Here, the authors obtain the distribution of absolute genetic risk for 15 common cancers, and they use a number of metrics to show that the genetic risk varies considerably across individuals.
format	article
author	Mats Julius Stensrud Morten Valberg
author_facet	Mats Julius Stensrud Morten Valberg
author_sort	Mats Julius Stensrud
title	Inequality in genetic cancer risk suggests bad genes rather than bad luck
title_short	Inequality in genetic cancer risk suggests bad genes rather than bad luck
title_full	Inequality in genetic cancer risk suggests bad genes rather than bad luck
title_fullStr	Inequality in genetic cancer risk suggests bad genes rather than bad luck
title_full_unstemmed	Inequality in genetic cancer risk suggests bad genes rather than bad luck
title_sort	inequality in genetic cancer risk suggests bad genes rather than bad luck
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/884a5552326249eeaac05b90fac62174
work_keys_str_mv	AT matsjuliusstensrud inequalityingeneticcancerrisksuggestsbadgenesratherthanbadluck AT mortenvalberg inequalityingeneticcancerrisksuggestsbadgenesratherthanbadluck
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Inequality in genetic cancer risk suggests bad genes rather than bad luck

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