Knockdown of anion exchanger 2 suppressed the growth of ovarian cancer cells via mTOR/p70S6K1 signaling
Abstract Anion exchanger 2 (AE2, encoded by SLC4A2) is a sodium-independent chloride/bicarbonate transporter and implicated in the regulation of intracellular pH and membrane potential. Previous studies have linked AE2 to the tumorigenesis of various cancers. Here, AE2 was identified as an up-regula...
Guardado en:
Autores principales: | Li-Jun Zhang, Renquan Lu, Ya-Nan Song, Jian-Yong Zhu, Wei Xia, Miao Zhang, Zhi-Yi Shao, Yan Huang, Yuqi Zhou, Hongqin Zhang, Lin Guo, Meiqin Zhang, Hong Zhang |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/884a62e5171a4872aaeebe1fa5c0f93e |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Fasting promotes acute hypoxic adaptation by suppressing mTOR-mediated pathways
por: Ruzhou Zhao, et al.
Publicado: (2021) -
mTOR controls ovarian follicle growth by regulating granulosa cell proliferation.
por: James Yu, et al.
Publicado: (2011) -
Fasting inhibits aerobic glycolysis and proliferation in colorectal cancer via the Fdft1-mediated AKT/mTOR/HIF1α pathway suppression
por: Mei-lin Weng, et al.
Publicado: (2020) -
Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response
por: Wenjun Wang, et al.
Publicado: (2021) -
mTOR inhibitors and risk of ovarian cysts: a systematic review and meta-analysis
por: Stefano Bianchi, et al.
Publicado: (2021)