A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface

The rapid appearance of mutations in circulating human influenza viruses and selection for escape from herd immunity require prediction of likely variants for an annual updating of influenza vaccines. The identification of human antibodies that recognize conserved surfaces on the influenza virus he...

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Autores principales:	Kevin R. McCarthy, Jiwon Lee, Akiko Watanabe, Masayuki Kuraoka, Lindsey R. Robinson-McCarthy, George Georgiou, Garnett Kelsoe, Stephen C. Harrison
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/88601486627b42309de4656ad1edf10c
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spelling	oai:doaj.org-article:88601486627b42309de4656ad1edf10c2021-11-03T21:15:04ZA Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface2150-751110.1128/mBio.01144-21https://doaj.org/article/88601486627b42309de4656ad1edf10c2021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01144-21https://doaj.org/toc/2150-7511 The rapid appearance of mutations in circulating human influenza viruses and selection for escape from herd immunity require prediction of likely variants for an annual updating of influenza vaccines. The identification of human antibodies that recognize conserved surfaces on the influenza virus hemagglutinin (HA) has prompted efforts to design immunogens that might selectively elicit such antibodies.Kevin R. McCarthyJiwon LeeAkiko WatanabeMasayuki KuraokaLindsey R. Robinson-McCarthyGeorge GeorgiouGarnett KelsoeStephen C. HarrisonAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 3 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Kevin R. McCarthy Jiwon Lee Akiko Watanabe Masayuki Kuraoka Lindsey R. Robinson-McCarthy George Georgiou Garnett Kelsoe Stephen C. Harrison A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface
description	The rapid appearance of mutations in circulating human influenza viruses and selection for escape from herd immunity require prediction of likely variants for an annual updating of influenza vaccines. The identification of human antibodies that recognize conserved surfaces on the influenza virus hemagglutinin (HA) has prompted efforts to design immunogens that might selectively elicit such antibodies.
format	article
author	Kevin R. McCarthy Jiwon Lee Akiko Watanabe Masayuki Kuraoka Lindsey R. Robinson-McCarthy George Georgiou Garnett Kelsoe Stephen C. Harrison
author_facet	Kevin R. McCarthy Jiwon Lee Akiko Watanabe Masayuki Kuraoka Lindsey R. Robinson-McCarthy George Georgiou Garnett Kelsoe Stephen C. Harrison
author_sort	Kevin R. McCarthy
title	A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface
title_short	A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface
title_full	A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface
title_fullStr	A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface
title_full_unstemmed	A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface
title_sort	prevalent focused human antibody response to the influenza virus hemagglutinin head interface
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/88601486627b42309de4656ad1edf10c
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A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface

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