Potential key bases of ribosomal RNA to kingdom-specific spectra of antibiotic susceptibility and the possible archaeal origin of eukaryotes.

In support of the hypothesis of the endosymbiotic origin of eukaryotes, much evidence has been found to support the idea that some organelles of eukaryotic cells originated from bacterial ancestors. Less attention has been paid to the identity of the host cell, although some biochemical and molecula...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Qiang Xie, Yanhui Wang, Jinzhong Lin, Yan Qin, Ying Wang, Wenjun Bu
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/886108521e8a4984a9a89d167d407889
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:886108521e8a4984a9a89d167d407889
record_format	dspace
spelling	oai:doaj.org-article:886108521e8a4984a9a89d167d4078892021-11-18T07:30:31ZPotential key bases of ribosomal RNA to kingdom-specific spectra of antibiotic susceptibility and the possible archaeal origin of eukaryotes.1932-620310.1371/journal.pone.0029468https://doaj.org/article/886108521e8a4984a9a89d167d4078892012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22247777/?tool=EBIhttps://doaj.org/toc/1932-6203In support of the hypothesis of the endosymbiotic origin of eukaryotes, much evidence has been found to support the idea that some organelles of eukaryotic cells originated from bacterial ancestors. Less attention has been paid to the identity of the host cell, although some biochemical and molecular genetic properties shared by archaea and eukaryotes have been documented. Through comparing 507 taxa of 16S-18S rDNA and 347 taxa of 23S-28S rDNA, we found that archaea and eukaryotes share twenty-six nucleotides signatures in ribosomal DNA. These signatures exist in all living eukaryotic organisms, whether protist, green plant, fungus, or animal. This evidence explicitly supports the archaeal origin of eukaryotes. In the ribosomal RNA, besides A2058 in Escherichia coli vs. G2400 in Saccharomyces cerevisiae, there still exist other twenties of sites, in which the bases are kingdom-specific. Some of these sites concentrate in the peptidyl transferase centre (PTC) of the 23S-28S rRNA. The results suggest potential key sites to explain the kingdom-specific spectra of drug resistance of ribosomes.Qiang XieYanhui WangJinzhong LinYan QinYing WangWenjun BuPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 1, p e29468 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Qiang Xie Yanhui Wang Jinzhong Lin Yan Qin Ying Wang Wenjun Bu Potential key bases of ribosomal RNA to kingdom-specific spectra of antibiotic susceptibility and the possible archaeal origin of eukaryotes.
description	In support of the hypothesis of the endosymbiotic origin of eukaryotes, much evidence has been found to support the idea that some organelles of eukaryotic cells originated from bacterial ancestors. Less attention has been paid to the identity of the host cell, although some biochemical and molecular genetic properties shared by archaea and eukaryotes have been documented. Through comparing 507 taxa of 16S-18S rDNA and 347 taxa of 23S-28S rDNA, we found that archaea and eukaryotes share twenty-six nucleotides signatures in ribosomal DNA. These signatures exist in all living eukaryotic organisms, whether protist, green plant, fungus, or animal. This evidence explicitly supports the archaeal origin of eukaryotes. In the ribosomal RNA, besides A2058 in Escherichia coli vs. G2400 in Saccharomyces cerevisiae, there still exist other twenties of sites, in which the bases are kingdom-specific. Some of these sites concentrate in the peptidyl transferase centre (PTC) of the 23S-28S rRNA. The results suggest potential key sites to explain the kingdom-specific spectra of drug resistance of ribosomes.
format	article
author	Qiang Xie Yanhui Wang Jinzhong Lin Yan Qin Ying Wang Wenjun Bu
author_facet	Qiang Xie Yanhui Wang Jinzhong Lin Yan Qin Ying Wang Wenjun Bu
author_sort	Qiang Xie
title	Potential key bases of ribosomal RNA to kingdom-specific spectra of antibiotic susceptibility and the possible archaeal origin of eukaryotes.
title_short	Potential key bases of ribosomal RNA to kingdom-specific spectra of antibiotic susceptibility and the possible archaeal origin of eukaryotes.
title_full	Potential key bases of ribosomal RNA to kingdom-specific spectra of antibiotic susceptibility and the possible archaeal origin of eukaryotes.
title_fullStr	Potential key bases of ribosomal RNA to kingdom-specific spectra of antibiotic susceptibility and the possible archaeal origin of eukaryotes.
title_full_unstemmed	Potential key bases of ribosomal RNA to kingdom-specific spectra of antibiotic susceptibility and the possible archaeal origin of eukaryotes.
title_sort	potential key bases of ribosomal rna to kingdom-specific spectra of antibiotic susceptibility and the possible archaeal origin of eukaryotes.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/886108521e8a4984a9a89d167d407889
work_keys_str_mv	AT qiangxie potentialkeybasesofribosomalrnatokingdomspecificspectraofantibioticsusceptibilityandthepossiblearchaealoriginofeukaryotes AT yanhuiwang potentialkeybasesofribosomalrnatokingdomspecificspectraofantibioticsusceptibilityandthepossiblearchaealoriginofeukaryotes AT jinzhonglin potentialkeybasesofribosomalrnatokingdomspecificspectraofantibioticsusceptibilityandthepossiblearchaealoriginofeukaryotes AT yanqin potentialkeybasesofribosomalrnatokingdomspecificspectraofantibioticsusceptibilityandthepossiblearchaealoriginofeukaryotes AT yingwang potentialkeybasesofribosomalrnatokingdomspecificspectraofantibioticsusceptibilityandthepossiblearchaealoriginofeukaryotes AT wenjunbu potentialkeybasesofribosomalrnatokingdomspecificspectraofantibioticsusceptibilityandthepossiblearchaealoriginofeukaryotes
_version_	1718423357383245824

Potential key bases of ribosomal RNA to kingdom-specific spectra of antibiotic susceptibility and the possible archaeal origin of eukaryotes.

Ejemplares similares