A transcriptomic atlas of aged human microglia
Aging is associated with various changes in the brain, including transcription alteration. Here, Bradshaw and colleagues describe the transcriptome of aged human cortical microglia, and show age-related gene expression as related to neurodegeneration.
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Nature Portfolio
2018
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oai:doaj.org-article:88714dece0ad45ec8217ad53d576eddd2021-12-02T14:40:32ZA transcriptomic atlas of aged human microglia10.1038/s41467-018-02926-52041-1723https://doaj.org/article/88714dece0ad45ec8217ad53d576eddd2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02926-5https://doaj.org/toc/2041-1723Aging is associated with various changes in the brain, including transcription alteration. Here, Bradshaw and colleagues describe the transcriptome of aged human cortical microglia, and show age-related gene expression as related to neurodegeneration.Marta OlahEllis PatrickAlexandra-Chloe VillaniJishu XuCharles C. WhiteKatie J. RyanPaul PiehowskiAlifiya KapasiParham NejadMaria CimpeanSarah ConnorChristina J. YungMichael FrangiehAllison McHenryWassim ElyamanVlad PetyukJulie A. SchneiderDavid A. BennettPhilip L. De JagerElizabeth M. BradshawNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Marta Olah Ellis Patrick Alexandra-Chloe Villani Jishu Xu Charles C. White Katie J. Ryan Paul Piehowski Alifiya Kapasi Parham Nejad Maria Cimpean Sarah Connor Christina J. Yung Michael Frangieh Allison McHenry Wassim Elyaman Vlad Petyuk Julie A. Schneider David A. Bennett Philip L. De Jager Elizabeth M. Bradshaw A transcriptomic atlas of aged human microglia |
| description |
Aging is associated with various changes in the brain, including transcription alteration. Here, Bradshaw and colleagues describe the transcriptome of aged human cortical microglia, and show age-related gene expression as related to neurodegeneration. |
| format |
article |
| author |
Marta Olah Ellis Patrick Alexandra-Chloe Villani Jishu Xu Charles C. White Katie J. Ryan Paul Piehowski Alifiya Kapasi Parham Nejad Maria Cimpean Sarah Connor Christina J. Yung Michael Frangieh Allison McHenry Wassim Elyaman Vlad Petyuk Julie A. Schneider David A. Bennett Philip L. De Jager Elizabeth M. Bradshaw |
| author_facet |
Marta Olah Ellis Patrick Alexandra-Chloe Villani Jishu Xu Charles C. White Katie J. Ryan Paul Piehowski Alifiya Kapasi Parham Nejad Maria Cimpean Sarah Connor Christina J. Yung Michael Frangieh Allison McHenry Wassim Elyaman Vlad Petyuk Julie A. Schneider David A. Bennett Philip L. De Jager Elizabeth M. Bradshaw |
| author_sort |
Marta Olah |
| title |
A transcriptomic atlas of aged human microglia |
| title_short |
A transcriptomic atlas of aged human microglia |
| title_full |
A transcriptomic atlas of aged human microglia |
| title_fullStr |
A transcriptomic atlas of aged human microglia |
| title_full_unstemmed |
A transcriptomic atlas of aged human microglia |
| title_sort |
transcriptomic atlas of aged human microglia |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/88714dece0ad45ec8217ad53d576eddd |
| work_keys_str_mv |
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1718390250612457472 |