Loss of the ciliary protein Chibby1 in mice leads to exocrine pancreatic degeneration and pancreatitis

Abstract Primary cilia protrude from the apical surface of many cell types and act as a sensory organelle that regulates diverse biological processes ranging from chemo- and mechanosensation to signaling. Ciliary dysfunction is associated with a wide array of genetic disorders, known as ciliopathies...

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Auteurs principaux: Benjamin Cyge, Vera Voronina, Mohammed Hoque, Eunice N. Kim, Jason Hall, Jennifer M. Bailey-Lundberg, Gregory J. Pazour, Howard C. Crawford, Randall T. Moon, Feng-Qian Li, Ken-Ichi Takemaru
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/887b15da67ff49449b0c627a4c5d0c9c
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