A functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics

Actin polymerization provides force for vital processes of the eukaryotic cell, but our understanding of actin dynamics and energetics remains limited due to the lack of high-quality probes. Here authors identify a family of highly sensitive fluorescent nucleotide analogues which bind to actin and p...

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Autores principales:	Jessica Colombo, Adrien Antkowiak, Konstantin Kogan, Tommi Kotila, Jenna Elliott, Audrey Guillotin, Pekka Lappalainen, Alphée Michelot
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/887eda43f8084479b43243044a31eee3
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spelling	oai:doaj.org-article:887eda43f8084479b43243044a31eee32021-12-02T14:19:04ZA functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics10.1038/s41467-020-20827-42041-1723https://doaj.org/article/887eda43f8084479b43243044a31eee32021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20827-4https://doaj.org/toc/2041-1723Actin polymerization provides force for vital processes of the eukaryotic cell, but our understanding of actin dynamics and energetics remains limited due to the lack of high-quality probes. Here authors identify a family of highly sensitive fluorescent nucleotide analogues which bind to actin and provide energy to power actin-based processes.Jessica ColomboAdrien AntkowiakKonstantin KoganTommi KotilaJenna ElliottAudrey GuillotinPekka LappalainenAlphée MichelotNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jessica Colombo Adrien Antkowiak Konstantin Kogan Tommi Kotila Jenna Elliott Audrey Guillotin Pekka Lappalainen Alphée Michelot A functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics
description	Actin polymerization provides force for vital processes of the eukaryotic cell, but our understanding of actin dynamics and energetics remains limited due to the lack of high-quality probes. Here authors identify a family of highly sensitive fluorescent nucleotide analogues which bind to actin and provide energy to power actin-based processes.
format	article
author	Jessica Colombo Adrien Antkowiak Konstantin Kogan Tommi Kotila Jenna Elliott Audrey Guillotin Pekka Lappalainen Alphée Michelot
author_facet	Jessica Colombo Adrien Antkowiak Konstantin Kogan Tommi Kotila Jenna Elliott Audrey Guillotin Pekka Lappalainen Alphée Michelot
author_sort	Jessica Colombo
title	A functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics
title_short	A functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics
title_full	A functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics
title_fullStr	A functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics
title_full_unstemmed	A functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics
title_sort	functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/887eda43f8084479b43243044a31eee3
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A functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics

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