No difference for changes in BMD between two different cementless hip stem designs 2 years after THA

Abstract This study evaluates how 2 different total hip arthroplasty (THA) stems compares regarding adaptive bone remodelling. The stems are both proximally porous coated, aiming for proximal fixation, but with different dispersal of the coating. They are also differently designed regarding the dist...

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Autores principales:	Karen Dyreborg, Søren Solgaard, Michael Skettrup, Michael Mørk Petersen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/888a7ecd51fa45a78765cb38ce27d7e3
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spelling	oai:doaj.org-article:888a7ecd51fa45a78765cb38ce27d7e32021-12-02T11:39:47ZNo difference for changes in BMD between two different cementless hip stem designs 2 years after THA10.1038/s41598-021-85424-x2045-2322https://doaj.org/article/888a7ecd51fa45a78765cb38ce27d7e32021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-85424-xhttps://doaj.org/toc/2045-2322Abstract This study evaluates how 2 different total hip arthroplasty (THA) stems compares regarding adaptive bone remodelling. The stems are both proximally porous coated, aiming for proximal fixation, but with different dispersal of the coating. They are also differently designed regarding the distal tip of the stem. We aimed to investigate if there is a difference in periprosthetic adaptive bone remodelling between two different designs. From February 2016 to September 2017, we randomised 62 patients, 1:1 (mean age = 64 years, Female/Male = 28/34), scheduled for an uncemented THA to receive either an EBM or a BM THA stem. We performed dual-energy x-ray absorptiometry (DEXA) scans within a week after surgery and at 3, 6, 12 and 24 months with measurements of bone mineral density (BMD) in the 7 Gruen zones (region of interest (ROI) 1–7). Additionally, Oxford Hip Score and Harris Hip Score were collected at 6, 12 and 24 months. We found a decrease in BMD between the postoperative and the 24-months values in all ROIs for both stems. The greatest decrease over time was seen for both groups in the ROI1 (BM = − 8.4%, p = 0.044, and EBM = − 6.5%, p = 0.001) and ROI7 (BM = − 7%, p = 0.005, and EBM = − 8.6%, p < 0.0005). We found a tendency in ROI2–4 of a higher degree of bone loss in the EBM group. However, this difference only continued beyond 6 months in ROI4 (24 months: BM = − 1.2% and EBM = − 2.8%, p = 0.001). The stems show similar adaptive bone remodelling and are clinically performing well.Karen DyreborgSøren SolgaardMichael SkettrupMichael Mørk PetersenNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Karen Dyreborg Søren Solgaard Michael Skettrup Michael Mørk Petersen No difference for changes in BMD between two different cementless hip stem designs 2 years after THA
description	Abstract This study evaluates how 2 different total hip arthroplasty (THA) stems compares regarding adaptive bone remodelling. The stems are both proximally porous coated, aiming for proximal fixation, but with different dispersal of the coating. They are also differently designed regarding the distal tip of the stem. We aimed to investigate if there is a difference in periprosthetic adaptive bone remodelling between two different designs. From February 2016 to September 2017, we randomised 62 patients, 1:1 (mean age = 64 years, Female/Male = 28/34), scheduled for an uncemented THA to receive either an EBM or a BM THA stem. We performed dual-energy x-ray absorptiometry (DEXA) scans within a week after surgery and at 3, 6, 12 and 24 months with measurements of bone mineral density (BMD) in the 7 Gruen zones (region of interest (ROI) 1–7). Additionally, Oxford Hip Score and Harris Hip Score were collected at 6, 12 and 24 months. We found a decrease in BMD between the postoperative and the 24-months values in all ROIs for both stems. The greatest decrease over time was seen for both groups in the ROI1 (BM = − 8.4%, p = 0.044, and EBM = − 6.5%, p = 0.001) and ROI7 (BM = − 7%, p = 0.005, and EBM = − 8.6%, p < 0.0005). We found a tendency in ROI2–4 of a higher degree of bone loss in the EBM group. However, this difference only continued beyond 6 months in ROI4 (24 months: BM = − 1.2% and EBM = − 2.8%, p = 0.001). The stems show similar adaptive bone remodelling and are clinically performing well.
format	article
author	Karen Dyreborg Søren Solgaard Michael Skettrup Michael Mørk Petersen
author_facet	Karen Dyreborg Søren Solgaard Michael Skettrup Michael Mørk Petersen
author_sort	Karen Dyreborg
title	No difference for changes in BMD between two different cementless hip stem designs 2 years after THA
title_short	No difference for changes in BMD between two different cementless hip stem designs 2 years after THA
title_full	No difference for changes in BMD between two different cementless hip stem designs 2 years after THA
title_fullStr	No difference for changes in BMD between two different cementless hip stem designs 2 years after THA
title_full_unstemmed	No difference for changes in BMD between two different cementless hip stem designs 2 years after THA
title_sort	no difference for changes in bmd between two different cementless hip stem designs 2 years after tha
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/888a7ecd51fa45a78765cb38ce27d7e3
work_keys_str_mv	AT karendyreborg nodifferenceforchangesinbmdbetweentwodifferentcementlesshipstemdesigns2yearsaftertha AT sørensolgaard nodifferenceforchangesinbmdbetweentwodifferentcementlesshipstemdesigns2yearsaftertha AT michaelskettrup nodifferenceforchangesinbmdbetweentwodifferentcementlesshipstemdesigns2yearsaftertha AT michaelmørkpetersen nodifferenceforchangesinbmdbetweentwodifferentcementlesshipstemdesigns2yearsaftertha
_version_	1718395710974459904

No difference for changes in BMD between two different cementless hip stem designs 2 years after THA

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