Open-label placebo treatment to improve relaxation training effects in healthy psychology students: a randomized controlled trial

Abstract Placebos, that are administered with deception, can reduce stress and increase relaxation. The present study investigated an open-label placebo (OLP) to improve the effects of Progressive Muscle Relaxation (PMR) training. A total of 160 psychology students were randomly assigned to a 14-day...

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Autores principales:	Anne Schienle, Isabella Unger
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/888ece7a7371447dab41b139b67a16ea
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spelling	oai:doaj.org-article:888ece7a7371447dab41b139b67a16ea2021-12-02T17:12:18ZOpen-label placebo treatment to improve relaxation training effects in healthy psychology students: a randomized controlled trial10.1038/s41598-021-92579-02045-2322https://doaj.org/article/888ece7a7371447dab41b139b67a16ea2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-92579-0https://doaj.org/toc/2045-2322Abstract Placebos, that are administered with deception, can reduce stress and increase relaxation. The present study investigated an open-label placebo (OLP) to improve the effects of Progressive Muscle Relaxation (PMR) training. A total of 160 psychology students were randomly assigned to a 14-day PMR course with or without daily OLP treatment. The placebo was administered along with an explanation of placebo effects and the verbal suggestion that the OLP activates the body’s natural relaxation response. The relaxation instructions for home practice were delivered via a smartphone app, which was also used for the evaluation of the exercises. The participants of the OLP group completed more PMR exercises (M = 9.75) than the group without a placebo (M = 8.15). The two groups did not differ in reported exercise-related changes in relaxation level. On average, the OLP group rated the effects of the placebo as very low and was characterized by a higher drop-out rate compared to the group without OLP. Some participants experienced the OLP as negative. In conclusion, factors that influence the acceptance of OLP treatment require further investigation.Anne SchienleIsabella UngerNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Anne Schienle Isabella Unger Open-label placebo treatment to improve relaxation training effects in healthy psychology students: a randomized controlled trial
description	Abstract Placebos, that are administered with deception, can reduce stress and increase relaxation. The present study investigated an open-label placebo (OLP) to improve the effects of Progressive Muscle Relaxation (PMR) training. A total of 160 psychology students were randomly assigned to a 14-day PMR course with or without daily OLP treatment. The placebo was administered along with an explanation of placebo effects and the verbal suggestion that the OLP activates the body’s natural relaxation response. The relaxation instructions for home practice were delivered via a smartphone app, which was also used for the evaluation of the exercises. The participants of the OLP group completed more PMR exercises (M = 9.75) than the group without a placebo (M = 8.15). The two groups did not differ in reported exercise-related changes in relaxation level. On average, the OLP group rated the effects of the placebo as very low and was characterized by a higher drop-out rate compared to the group without OLP. Some participants experienced the OLP as negative. In conclusion, factors that influence the acceptance of OLP treatment require further investigation.
format	article
author	Anne Schienle Isabella Unger
author_facet	Anne Schienle Isabella Unger
author_sort	Anne Schienle
title	Open-label placebo treatment to improve relaxation training effects in healthy psychology students: a randomized controlled trial
title_short	Open-label placebo treatment to improve relaxation training effects in healthy psychology students: a randomized controlled trial
title_full	Open-label placebo treatment to improve relaxation training effects in healthy psychology students: a randomized controlled trial
title_fullStr	Open-label placebo treatment to improve relaxation training effects in healthy psychology students: a randomized controlled trial
title_full_unstemmed	Open-label placebo treatment to improve relaxation training effects in healthy psychology students: a randomized controlled trial
title_sort	open-label placebo treatment to improve relaxation training effects in healthy psychology students: a randomized controlled trial
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/888ece7a7371447dab41b139b67a16ea
work_keys_str_mv	AT anneschienle openlabelplacebotreatmenttoimproverelaxationtrainingeffectsinhealthypsychologystudentsarandomizedcontrolledtrial AT isabellaunger openlabelplacebotreatmenttoimproverelaxationtrainingeffectsinhealthypsychologystudentsarandomizedcontrolledtrial
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Open-label placebo treatment to improve relaxation training effects in healthy psychology students: a randomized controlled trial

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