The structure of an archaeal oligosaccharyltransferase provides insight into the strict exclusion of proline from the N-glycosylation sequon

Yuya Taguchi, Takahiro Yamasaki, et al. determined the crystal structure of the oligosaccharyltransferase enzyme, OST, from Aechaeoglobus fulgidus, in a complex with two substrates. Their work provides valuable insight into the sequon specificity of N-glycosylation, which is a major posttranslationa...

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Autores principales: Yuya Taguchi, Takahiro Yamasaki, Marie Ishikawa, Yuki Kawasaki, Ryuji Yukimura, Maki Mitani, Kunio Hirata, Daisuke Kohda
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/88947496abf54cb3adebc7c19c8b5b65
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spelling oai:doaj.org-article:88947496abf54cb3adebc7c19c8b5b652021-12-02T16:35:41ZThe structure of an archaeal oligosaccharyltransferase provides insight into the strict exclusion of proline from the N-glycosylation sequon10.1038/s42003-021-02473-82399-3642https://doaj.org/article/88947496abf54cb3adebc7c19c8b5b652021-08-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02473-8https://doaj.org/toc/2399-3642Yuya Taguchi, Takahiro Yamasaki, et al. determined the crystal structure of the oligosaccharyltransferase enzyme, OST, from Aechaeoglobus fulgidus, in a complex with two substrates. Their work provides valuable insight into the sequon specificity of N-glycosylation, which is a major posttranslational modification across eukaryotes.Yuya TaguchiTakahiro YamasakiMarie IshikawaYuki KawasakiRyuji YukimuraMaki MitaniKunio HirataDaisuke KohdaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Yuya Taguchi
Takahiro Yamasaki
Marie Ishikawa
Yuki Kawasaki
Ryuji Yukimura
Maki Mitani
Kunio Hirata
Daisuke Kohda
The structure of an archaeal oligosaccharyltransferase provides insight into the strict exclusion of proline from the N-glycosylation sequon
description Yuya Taguchi, Takahiro Yamasaki, et al. determined the crystal structure of the oligosaccharyltransferase enzyme, OST, from Aechaeoglobus fulgidus, in a complex with two substrates. Their work provides valuable insight into the sequon specificity of N-glycosylation, which is a major posttranslational modification across eukaryotes.
format article
author Yuya Taguchi
Takahiro Yamasaki
Marie Ishikawa
Yuki Kawasaki
Ryuji Yukimura
Maki Mitani
Kunio Hirata
Daisuke Kohda
author_facet Yuya Taguchi
Takahiro Yamasaki
Marie Ishikawa
Yuki Kawasaki
Ryuji Yukimura
Maki Mitani
Kunio Hirata
Daisuke Kohda
author_sort Yuya Taguchi
title The structure of an archaeal oligosaccharyltransferase provides insight into the strict exclusion of proline from the N-glycosylation sequon
title_short The structure of an archaeal oligosaccharyltransferase provides insight into the strict exclusion of proline from the N-glycosylation sequon
title_full The structure of an archaeal oligosaccharyltransferase provides insight into the strict exclusion of proline from the N-glycosylation sequon
title_fullStr The structure of an archaeal oligosaccharyltransferase provides insight into the strict exclusion of proline from the N-glycosylation sequon
title_full_unstemmed The structure of an archaeal oligosaccharyltransferase provides insight into the strict exclusion of proline from the N-glycosylation sequon
title_sort structure of an archaeal oligosaccharyltransferase provides insight into the strict exclusion of proline from the n-glycosylation sequon
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/88947496abf54cb3adebc7c19c8b5b65
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