Modulation of extrasynaptic GABAA alpha 5 receptors in the ventral hippocampus normalizes physiological and behavioral deficits in a circuit specific manner
Region-specific increases in hippocampal activity have been reported in schizophrenia patients, yet there are little known about how these circuit levels changes modulate behavioral deficits. Here authors found that that over-expression of the a5 subunit of the GABAA receptor increased tonic GABA cu...
Saved in:
Main Authors: | J. J. Donegan, A. M. Boley, J. Yamaguchi, G. M. Toney, D. J. Lodge |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
|
Subjects: | |
Online Access: | https://doaj.org/article/88a171ca370b4e079062da3a38e3caff |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Tau is required for the function of extrasynaptic NMDA receptors
by: Noemí Pallas-Bazarra, et al.
Published: (2019) -
Top-down modulation of olfactory-guided behaviours by the anterior olfactory nucleus pars medialis and ventral hippocampus
by: Afif J. Aqrabawi, et al.
Published: (2016) -
Physiological role for GABAA receptor desensitization in the induction of long-term potentiation at inhibitory synapses
by: Martin Field, et al.
Published: (2021) -
Developmental alterations in the transcriptome of three distinct rodent models of schizophrenia.
by: Jennifer J Donegan, et al.
Published: (2020) -
Extrasynaptic NMDA receptor dependent long-term potentiation of hippocampal CA1 pyramidal neurons
by: Qian Yang, et al.
Published: (2017)