Alkyl halides as both hydride and alkyl sources in catalytic regioselective reductive olefin hydroalkylation
Methods that regioselectively install a functionalized alkyl unit at the 2-position of a terminal unactivated C=C bond are scarce. Here, the authors report a Markovnikov-selective hydroalkylation of unactivated amide-tethered alkenes catalyzed by nickel in conjunction with a stoichiometric reductant...
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Auteurs principaux: | Xianxiao Chen, Weidong Rao, Tao Yang, Ming Joo Koh |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2020
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Sujets: | |
Accès en ligne: | https://doaj.org/article/88a744a3686041109c4ea736e41cbe54 |
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