Genomic landscape of extraordinary responses in metastatic breast cancer

Lim, Kim and Jung et al. report a whole-exome sequence analysis of 30 Korean patients showing extreme treatment responses for metastatic breast cancer. They find that compared to non-responders, extreme responders have fewer nonsynonymous mutations and copy number variants.

Guardado en:
Detalles Bibliográficos
Autores principales: Sun Min Lim, Eunyoung Kim, Kyung Hae Jung, Sora Kim, Ja Seung Koo, Seung Il Kim, Seho Park, Hyung Seok Park, Byoung Woo Park, Young Up Cho, Ji Ye Kim, Soonmyung Paik, Nak-Jung Kwon, Gun Min Kim, Ji Hyoung Kim, Min Hwan Kim, Min Kyung Jeon, Sangwoo Kim, Joohyuk Sohn
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Acceso en línea:https://doaj.org/article/88ab653ac0f34cc590341be94ab057d0
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:88ab653ac0f34cc590341be94ab057d0
record_format dspace
spelling oai:doaj.org-article:88ab653ac0f34cc590341be94ab057d02021-12-02T14:17:15ZGenomic landscape of extraordinary responses in metastatic breast cancer10.1038/s42003-021-01973-x2399-3642https://doaj.org/article/88ab653ac0f34cc590341be94ab057d02021-04-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01973-xhttps://doaj.org/toc/2399-3642Lim, Kim and Jung et al. report a whole-exome sequence analysis of 30 Korean patients showing extreme treatment responses for metastatic breast cancer. They find that compared to non-responders, extreme responders have fewer nonsynonymous mutations and copy number variants.Sun Min LimEunyoung KimKyung Hae JungSora KimJa Seung KooSeung Il KimSeho ParkHyung Seok ParkByoung Woo ParkYoung Up ChoJi Ye KimSoonmyung PaikNak-Jung KwonGun Min KimJi Hyoung KimMin Hwan KimMin Kyung JeonSangwoo KimJoohyuk SohnNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Sun Min Lim
Eunyoung Kim
Kyung Hae Jung
Sora Kim
Ja Seung Koo
Seung Il Kim
Seho Park
Hyung Seok Park
Byoung Woo Park
Young Up Cho
Ji Ye Kim
Soonmyung Paik
Nak-Jung Kwon
Gun Min Kim
Ji Hyoung Kim
Min Hwan Kim
Min Kyung Jeon
Sangwoo Kim
Joohyuk Sohn
Genomic landscape of extraordinary responses in metastatic breast cancer
description Lim, Kim and Jung et al. report a whole-exome sequence analysis of 30 Korean patients showing extreme treatment responses for metastatic breast cancer. They find that compared to non-responders, extreme responders have fewer nonsynonymous mutations and copy number variants.
format article
author Sun Min Lim
Eunyoung Kim
Kyung Hae Jung
Sora Kim
Ja Seung Koo
Seung Il Kim
Seho Park
Hyung Seok Park
Byoung Woo Park
Young Up Cho
Ji Ye Kim
Soonmyung Paik
Nak-Jung Kwon
Gun Min Kim
Ji Hyoung Kim
Min Hwan Kim
Min Kyung Jeon
Sangwoo Kim
Joohyuk Sohn
author_facet Sun Min Lim
Eunyoung Kim
Kyung Hae Jung
Sora Kim
Ja Seung Koo
Seung Il Kim
Seho Park
Hyung Seok Park
Byoung Woo Park
Young Up Cho
Ji Ye Kim
Soonmyung Paik
Nak-Jung Kwon
Gun Min Kim
Ji Hyoung Kim
Min Hwan Kim
Min Kyung Jeon
Sangwoo Kim
Joohyuk Sohn
author_sort Sun Min Lim
title Genomic landscape of extraordinary responses in metastatic breast cancer
title_short Genomic landscape of extraordinary responses in metastatic breast cancer
title_full Genomic landscape of extraordinary responses in metastatic breast cancer
title_fullStr Genomic landscape of extraordinary responses in metastatic breast cancer
title_full_unstemmed Genomic landscape of extraordinary responses in metastatic breast cancer
title_sort genomic landscape of extraordinary responses in metastatic breast cancer
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/88ab653ac0f34cc590341be94ab057d0
work_keys_str_mv AT sunminlim genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
AT eunyoungkim genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
AT kyunghaejung genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
AT sorakim genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
AT jaseungkoo genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
AT seungilkim genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
AT sehopark genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
AT hyungseokpark genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
AT byoungwoopark genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
AT youngupcho genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
AT jiyekim genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
AT soonmyungpaik genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
AT nakjungkwon genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
AT gunminkim genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
AT jihyoungkim genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
AT minhwankim genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
AT minkyungjeon genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
AT sangwookim genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
AT joohyuksohn genomiclandscapeofextraordinaryresponsesinmetastaticbreastcancer
_version_ 1718391617759477760