Organozinc pivalates for cobalt-catalyzed difluoroalkylarylation of alkenes

Transition metal-catalyzed regioselective difunctionalizations of alkenes with two different functional groups are useful for preparing organic compounds, but the construction of two new C–C bonds is challenging. Here, the authors report cobalt-catalyzed regioselective difluoroalkylarylation of alke...

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Autores principales:	Xinyi Cheng, Xingchen Liu, Shengchun Wang, Ying Hu, Binjing Hu, Aiwen Lei, Jie Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/88ac605eaf024df4a82ff824a61ceb75
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spelling	oai:doaj.org-article:88ac605eaf024df4a82ff824a61ceb752021-12-02T18:37:05ZOrganozinc pivalates for cobalt-catalyzed difluoroalkylarylation of alkenes10.1038/s41467-021-24596-62041-1723https://doaj.org/article/88ac605eaf024df4a82ff824a61ceb752021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24596-6https://doaj.org/toc/2041-1723Transition metal-catalyzed regioselective difunctionalizations of alkenes with two different functional groups are useful for preparing organic compounds, but the construction of two new C–C bonds is challenging. Here, the authors report cobalt-catalyzed regioselective difluoroalkylarylation of alkenes with solid arylzinc pivalates and difluoroalkyl bromides, through a cascade Csp3 ‒Csp3/Csp3 ‒Csp2 bond formation.Xinyi ChengXingchen LiuShengchun WangYing HuBinjing HuAiwen LeiJie LiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xinyi Cheng Xingchen Liu Shengchun Wang Ying Hu Binjing Hu Aiwen Lei Jie Li Organozinc pivalates for cobalt-catalyzed difluoroalkylarylation of alkenes
description	Transition metal-catalyzed regioselective difunctionalizations of alkenes with two different functional groups are useful for preparing organic compounds, but the construction of two new C–C bonds is challenging. Here, the authors report cobalt-catalyzed regioselective difluoroalkylarylation of alkenes with solid arylzinc pivalates and difluoroalkyl bromides, through a cascade Csp3 ‒Csp3/Csp3 ‒Csp2 bond formation.
format	article
author	Xinyi Cheng Xingchen Liu Shengchun Wang Ying Hu Binjing Hu Aiwen Lei Jie Li
author_facet	Xinyi Cheng Xingchen Liu Shengchun Wang Ying Hu Binjing Hu Aiwen Lei Jie Li
author_sort	Xinyi Cheng
title	Organozinc pivalates for cobalt-catalyzed difluoroalkylarylation of alkenes
title_short	Organozinc pivalates for cobalt-catalyzed difluoroalkylarylation of alkenes
title_full	Organozinc pivalates for cobalt-catalyzed difluoroalkylarylation of alkenes
title_fullStr	Organozinc pivalates for cobalt-catalyzed difluoroalkylarylation of alkenes
title_full_unstemmed	Organozinc pivalates for cobalt-catalyzed difluoroalkylarylation of alkenes
title_sort	organozinc pivalates for cobalt-catalyzed difluoroalkylarylation of alkenes
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/88ac605eaf024df4a82ff824a61ceb75
work_keys_str_mv	AT xinyicheng organozincpivalatesforcobaltcatalyzeddifluoroalkylarylationofalkenes AT xingchenliu organozincpivalatesforcobaltcatalyzeddifluoroalkylarylationofalkenes AT shengchunwang organozincpivalatesforcobaltcatalyzeddifluoroalkylarylationofalkenes AT yinghu organozincpivalatesforcobaltcatalyzeddifluoroalkylarylationofalkenes AT binjinghu organozincpivalatesforcobaltcatalyzeddifluoroalkylarylationofalkenes AT aiwenlei organozincpivalatesforcobaltcatalyzeddifluoroalkylarylationofalkenes AT jieli organozincpivalatesforcobaltcatalyzeddifluoroalkylarylationofalkenes
_version_	1718377872921460736

Organozinc pivalates for cobalt-catalyzed difluoroalkylarylation of alkenes

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