Electrocatalytic determination of levodopa in presence of cabergoline using carbon paste electrode modified with graphene quantum dots/2-chlorobenzoyl ferrocene/ionic liquid

The electrochemical sensor was fabricated for the simultaneous determination of levodopa and cabergoline using carbon paste electrode (CPE) modified with graphene quantum dots (GQD), 2-chlorobenzoyl ferrocene (2CBF) and ionic liquid (IL). Then, the electrochemical behavior of levodopa alone and sim...

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Autor principal:	Peyman Mohammadzadeh Jahani
Formato:	article
Lenguaje:	EN
Publicado:	International Association of Physical Chemists (IAPC) 2021
Materias:	Electrochemical sensor chemically modified electrode levodopa cabergoline Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/88b57abbde0744bfa6195c930c57aa34
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spelling	oai:doaj.org-article:88b57abbde0744bfa6195c930c57aa342021-11-18T10:07:25ZElectrocatalytic determination of levodopa in presence of cabergoline using carbon paste electrode modified with graphene quantum dots/2-chlorobenzoyl ferrocene/ionic liquid10.5599/jese.11331847-9286https://doaj.org/article/88b57abbde0744bfa6195c930c57aa342021-11-01T00:00:00Zhttp://pub.iapchem.org/ojs/index.php/JESE/article/view/1133https://doaj.org/toc/1847-9286 The electrochemical sensor was fabricated for the simultaneous determination of levodopa and cabergoline using carbon paste electrode (CPE) modified with graphene quantum dots (GQD), 2-chlorobenzoyl ferrocene (2CBF) and ionic liquid (IL). Then, the electrochemical behavior of levodopa alone and simultaneously with cabergoline at the surface of GQDs/2CBF/IL/CPE was investigated in phosphate buffer solution (PBS). Under optimal PBS, pH=7 condition, oxidation peak current has been found proportional to levodopa concentration in the range between 0.07 μM and 500.0 μM, with the limit of detection (LOD) of 0.02 μM (S/N=3). Outputs showed that at GQDs/2CBF/IL/CPE surface, the levodopa and cabergoline oxidation peaks are separated by the potential difference of 200 mV. In addition, it was found that this modified electrode possesses acceptable sensitivity, selectivity, stability and repeatability. All these properties were sufficient to allow simultaneous detection of levodopa and cabergoline in real samples at the surface of GQDs/2CBF/IL/CPE. This was supported by the successful application of this electrochemical sensor electrode for the determination of levodopa and cabergoline in urine, serum, and cabergoline tablets. Peyman Mohammadzadeh JahaniInternational Association of Physical Chemists (IAPC)articleElectrochemical sensorchemically modified electrodelevodopacabergolineChemistryQD1-999ENJournal of Electrochemical Science and Engineering, Vol 11, Iss 3 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Electrochemical sensor chemically modified electrode levodopa cabergoline Chemistry QD1-999
spellingShingle	Electrochemical sensor chemically modified electrode levodopa cabergoline Chemistry QD1-999 Peyman Mohammadzadeh Jahani Electrocatalytic determination of levodopa in presence of cabergoline using carbon paste electrode modified with graphene quantum dots/2-chlorobenzoyl ferrocene/ionic liquid
description	The electrochemical sensor was fabricated for the simultaneous determination of levodopa and cabergoline using carbon paste electrode (CPE) modified with graphene quantum dots (GQD), 2-chlorobenzoyl ferrocene (2CBF) and ionic liquid (IL). Then, the electrochemical behavior of levodopa alone and simultaneously with cabergoline at the surface of GQDs/2CBF/IL/CPE was investigated in phosphate buffer solution (PBS). Under optimal PBS, pH=7 condition, oxidation peak current has been found proportional to levodopa concentration in the range between 0.07 μM and 500.0 μM, with the limit of detection (LOD) of 0.02 μM (S/N=3). Outputs showed that at GQDs/2CBF/IL/CPE surface, the levodopa and cabergoline oxidation peaks are separated by the potential difference of 200 mV. In addition, it was found that this modified electrode possesses acceptable sensitivity, selectivity, stability and repeatability. All these properties were sufficient to allow simultaneous detection of levodopa and cabergoline in real samples at the surface of GQDs/2CBF/IL/CPE. This was supported by the successful application of this electrochemical sensor electrode for the determination of levodopa and cabergoline in urine, serum, and cabergoline tablets.
format	article
author	Peyman Mohammadzadeh Jahani
author_facet	Peyman Mohammadzadeh Jahani
author_sort	Peyman Mohammadzadeh Jahani
title	Electrocatalytic determination of levodopa in presence of cabergoline using carbon paste electrode modified with graphene quantum dots/2-chlorobenzoyl ferrocene/ionic liquid
title_short	Electrocatalytic determination of levodopa in presence of cabergoline using carbon paste electrode modified with graphene quantum dots/2-chlorobenzoyl ferrocene/ionic liquid
title_full	Electrocatalytic determination of levodopa in presence of cabergoline using carbon paste electrode modified with graphene quantum dots/2-chlorobenzoyl ferrocene/ionic liquid
title_fullStr	Electrocatalytic determination of levodopa in presence of cabergoline using carbon paste electrode modified with graphene quantum dots/2-chlorobenzoyl ferrocene/ionic liquid
title_full_unstemmed	Electrocatalytic determination of levodopa in presence of cabergoline using carbon paste electrode modified with graphene quantum dots/2-chlorobenzoyl ferrocene/ionic liquid
title_sort	electrocatalytic determination of levodopa in presence of cabergoline using carbon paste electrode modified with graphene quantum dots/2-chlorobenzoyl ferrocene/ionic liquid
publisher	International Association of Physical Chemists (IAPC)
publishDate	2021
url	https://doaj.org/article/88b57abbde0744bfa6195c930c57aa34
work_keys_str_mv	AT peymanmohammadzadehjahani electrocatalyticdeterminationoflevodopainpresenceofcabergolineusingcarbonpasteelectrodemodifiedwithgraphenequantumdots2chlorobenzoylferroceneionicliquid
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Electrocatalytic determination of levodopa in presence of cabergoline using carbon paste electrode modified with graphene quantum dots/2-chlorobenzoyl ferrocene/ionic liquid

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