Epithelioid hemangioma of liver—The first reported case

Epithelioid hemangioma, otherwise known as angiolymphoid hyperplasia with eosinophilia, is a rare benign vasoproliferative disease with an unknown etiology. We report the case of a 42-year-old man with routine bloods test showing mildly elevated serum bilirubin level. CT scan revealed a lesion in th...

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Autores principales:	Adrienn Biro, László Ternyik, Veronika Czoma, Géza Hegedűs, István Bálint, Dezső Tóth, Zsolt Káposztás
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	angiolymphoid hyperplasia with eosinophilia epithelioid hemangioma liver Pathology RB1-214 Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/88b6d9eb12eb489faab76ae2b5af9dca
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spelling	oai:doaj.org-article:88b6d9eb12eb489faab76ae2b5af9dca2021-12-02T17:28:22ZEpithelioid hemangioma of liver—The first reported case0377-492910.4103/IJPM.IJPM_148_20https://doaj.org/article/88b6d9eb12eb489faab76ae2b5af9dca2021-01-01T00:00:00Zhttp://www.ijpmonline.org/article.asp?issn=0377-4929;year=2021;volume=64;issue=5;spage=143;epage=145;aulast=Birohttps://doaj.org/toc/0377-4929Epithelioid hemangioma, otherwise known as angiolymphoid hyperplasia with eosinophilia, is a rare benign vasoproliferative disease with an unknown etiology. We report the case of a 42-year-old man with routine bloods test showing mildly elevated serum bilirubin level. CT scan revealed a lesion in the left liver lobe not typical of FNH. PET/CT scan and a dynamic liver MRI were consistent with a malignant mass. Surgical resection was performed. Histopathology of the 45 mm mass reported well-defined, slightly lobular proliferations of capillary-sized vessels around several central muscular vessels. Although the endothelial cells revealed a “hobnail” appearance, none of them showed pleomorphism or mitotic activity. Endothelial cells showed reactivity for the endothelial markers (CD34, CD31) and smooth muscle was detected in the blood vessel walls via immunohistochemistry. Despite its benign nature, epithelioid hemangioma of the liver can lead to a diagnostic and therapeutic dilemma due to the malignant looking features on imaging modalities.Adrienn BiroLászló TernyikVeronika CzomaGéza HegedűsIstván BálintDezső TóthZsolt KáposztásWolters Kluwer Medknow Publicationsarticleangiolymphoid hyperplasia with eosinophiliaepithelioid hemangiomaliverPathologyRB1-214MicrobiologyQR1-502ENIndian Journal of Pathology and Microbiology, Vol 64, Iss 5, Pp 143-145 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	angiolymphoid hyperplasia with eosinophilia epithelioid hemangioma liver Pathology RB1-214 Microbiology QR1-502
spellingShingle	angiolymphoid hyperplasia with eosinophilia epithelioid hemangioma liver Pathology RB1-214 Microbiology QR1-502 Adrienn Biro László Ternyik Veronika Czoma Géza Hegedűs István Bálint Dezső Tóth Zsolt Káposztás Epithelioid hemangioma of liver—The first reported case
description	Epithelioid hemangioma, otherwise known as angiolymphoid hyperplasia with eosinophilia, is a rare benign vasoproliferative disease with an unknown etiology. We report the case of a 42-year-old man with routine bloods test showing mildly elevated serum bilirubin level. CT scan revealed a lesion in the left liver lobe not typical of FNH. PET/CT scan and a dynamic liver MRI were consistent with a malignant mass. Surgical resection was performed. Histopathology of the 45 mm mass reported well-defined, slightly lobular proliferations of capillary-sized vessels around several central muscular vessels. Although the endothelial cells revealed a “hobnail” appearance, none of them showed pleomorphism or mitotic activity. Endothelial cells showed reactivity for the endothelial markers (CD34, CD31) and smooth muscle was detected in the blood vessel walls via immunohistochemistry. Despite its benign nature, epithelioid hemangioma of the liver can lead to a diagnostic and therapeutic dilemma due to the malignant looking features on imaging modalities.
format	article
author	Adrienn Biro László Ternyik Veronika Czoma Géza Hegedűs István Bálint Dezső Tóth Zsolt Káposztás
author_facet	Adrienn Biro László Ternyik Veronika Czoma Géza Hegedűs István Bálint Dezső Tóth Zsolt Káposztás
author_sort	Adrienn Biro
title	Epithelioid hemangioma of liver—The first reported case
title_short	Epithelioid hemangioma of liver—The first reported case
title_full	Epithelioid hemangioma of liver—The first reported case
title_fullStr	Epithelioid hemangioma of liver—The first reported case
title_full_unstemmed	Epithelioid hemangioma of liver—The first reported case
title_sort	epithelioid hemangioma of liver—the first reported case
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/88b6d9eb12eb489faab76ae2b5af9dca
work_keys_str_mv	AT adriennbiro epithelioidhemangiomaofliverthefirstreportedcase AT laszloternyik epithelioidhemangiomaofliverthefirstreportedcase AT veronikaczoma epithelioidhemangiomaofliverthefirstreportedcase AT gezahegedus epithelioidhemangiomaofliverthefirstreportedcase AT istvanbalint epithelioidhemangiomaofliverthefirstreportedcase AT dezsototh epithelioidhemangiomaofliverthefirstreportedcase AT zsoltkaposztas epithelioidhemangiomaofliverthefirstreportedcase
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Epithelioid hemangioma of liver—The first reported case

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