Effects of Breed/Species and Gender on Platelet Concentration in Autologous Platelet Rich Plasma

Platelet rich plasma (PRP) is an autologous biological product harvested by consecutive centrifugations of whole blood and separation of plasma in a stepwise protocol. PRP has been successfully used to stimulate healing in orthopedic and dermatological conditions, both in humans and animals. The pri...

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Autores principales:	Miranda Stephania, De Mello Costa Maria Fernanda, Jeunon Senna Juliana, Frapoint João Castañon, De Alencar Nayro Xavier, Barroso Lessa Daniel Augusto
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2018
Materias:	biological products blood platelets horses methods Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/88ba0f82c06c4c2395f1c3cddabaed57
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spelling	oai:doaj.org-article:88ba0f82c06c4c2395f1c3cddabaed572021-11-17T21:27:53ZEffects of Breed/Species and Gender on Platelet Concentration in Autologous Platelet Rich Plasma1820-744810.2478/acve-2018-0038https://doaj.org/article/88ba0f82c06c4c2395f1c3cddabaed572018-12-01T00:00:00Zhttps://doi.org/10.2478/acve-2018-0038https://doaj.org/toc/1820-7448Platelet rich plasma (PRP) is an autologous biological product harvested by consecutive centrifugations of whole blood and separation of plasma in a stepwise protocol. PRP has been successfully used to stimulate healing in orthopedic and dermatological conditions, both in humans and animals. The principle is the fact that α- granules inside platelets contain a high concentration of growth factors, that once released can interfere with cellular communication and speed up healing. Standardization of PRP requires establishing a gold standard for the preparation and evaluation of the product, especially considering that platelet concentration and, therefore, growth factor concentration, might vary due to a number of variables. Factors such as age, gender, race or breed, and immune status of the patient might interfere with PRP quality and with treatment results, although little is known about such interferences. This research investigated the effect of breed/species and gender in platelet concentration in autologous PRP from horses and mules. The results demonstrate that Quarter Horses provided PRP with the greatest amount of platelets, although mules had a higher concentration percentages in relation to the initial platelet counts.Miranda StephaniaDe Mello Costa Maria FernandaJeunon Senna JulianaFrapoint João CastañonDe Alencar Nayro XavierBarroso Lessa Daniel AugustoSciendoarticlebiological productsblood plateletshorsesmethodsVeterinary medicineSF600-1100ENActa Veterinaria, Vol 68, Iss 4, Pp 474-483 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	biological products blood platelets horses methods Veterinary medicine SF600-1100
spellingShingle	biological products blood platelets horses methods Veterinary medicine SF600-1100 Miranda Stephania De Mello Costa Maria Fernanda Jeunon Senna Juliana Frapoint João Castañon De Alencar Nayro Xavier Barroso Lessa Daniel Augusto Effects of Breed/Species and Gender on Platelet Concentration in Autologous Platelet Rich Plasma
description	Platelet rich plasma (PRP) is an autologous biological product harvested by consecutive centrifugations of whole blood and separation of plasma in a stepwise protocol. PRP has been successfully used to stimulate healing in orthopedic and dermatological conditions, both in humans and animals. The principle is the fact that α- granules inside platelets contain a high concentration of growth factors, that once released can interfere with cellular communication and speed up healing. Standardization of PRP requires establishing a gold standard for the preparation and evaluation of the product, especially considering that platelet concentration and, therefore, growth factor concentration, might vary due to a number of variables. Factors such as age, gender, race or breed, and immune status of the patient might interfere with PRP quality and with treatment results, although little is known about such interferences. This research investigated the effect of breed/species and gender in platelet concentration in autologous PRP from horses and mules. The results demonstrate that Quarter Horses provided PRP with the greatest amount of platelets, although mules had a higher concentration percentages in relation to the initial platelet counts.
format	article
author	Miranda Stephania De Mello Costa Maria Fernanda Jeunon Senna Juliana Frapoint João Castañon De Alencar Nayro Xavier Barroso Lessa Daniel Augusto
author_facet	Miranda Stephania De Mello Costa Maria Fernanda Jeunon Senna Juliana Frapoint João Castañon De Alencar Nayro Xavier Barroso Lessa Daniel Augusto
author_sort	Miranda Stephania
title	Effects of Breed/Species and Gender on Platelet Concentration in Autologous Platelet Rich Plasma
title_short	Effects of Breed/Species and Gender on Platelet Concentration in Autologous Platelet Rich Plasma
title_full	Effects of Breed/Species and Gender on Platelet Concentration in Autologous Platelet Rich Plasma
title_fullStr	Effects of Breed/Species and Gender on Platelet Concentration in Autologous Platelet Rich Plasma
title_full_unstemmed	Effects of Breed/Species and Gender on Platelet Concentration in Autologous Platelet Rich Plasma
title_sort	effects of breed/species and gender on platelet concentration in autologous platelet rich plasma
publisher	Sciendo
publishDate	2018
url	https://doaj.org/article/88ba0f82c06c4c2395f1c3cddabaed57
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Effects of Breed/Species and Gender on Platelet Concentration in Autologous Platelet Rich Plasma

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