The immune response to the novel coronavirus infection

This review summarizes the current knowledge on the humoral and T-cell immunity to the novel coronavirus infection. A special attention is paid to the viral proteins that induce production of antibodies, different types of immunoglobulins and their role in the protection against the virus as well as...

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Autores principales:	Vyacheslav S. Fedorov, Olga N. Ivanova, Inna L. Karpenko, Alexander V. Ivanov
Formato:	article
Lenguaje:	RU
Publicado:	Eco-vector 2021
Materias:	coronavirus sars-cov-2 immunity antibodies t-cell response Medicine R
Acceso en línea:	https://doaj.org/article/88bb358e624841668196f2044d9cde44
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id	oai:doaj.org-article:88bb358e624841668196f2044d9cde44
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spelling	oai:doaj.org-article:88bb358e624841668196f2044d9cde442021-11-30T18:15:21ZThe immune response to the novel coronavirus infection2220-30952618-862710.17816/clinpract64677https://doaj.org/article/88bb358e624841668196f2044d9cde442021-03-01T00:00:00Zhttps://journals.eco-vector.com/clinpractice/article/viewFile/64677/pdfhttps://doaj.org/toc/2220-3095https://doaj.org/toc/2618-8627This review summarizes the current knowledge on the humoral and T-cell immunity to the novel coronavirus infection. A special attention is paid to the viral proteins that induce production of antibodies, different types of immunoglobulins and their role in the protection against the virus as well as to the duration of the humoral immune response. In addition, a concise analysis of the T-cell immunity status during COVID-19 and its input into the antiviral defense is presented. The collected data demonstrating preservation of both the humoral and T-cell immunity are urgently needed in the medical professionals' community for evidence-based decisions on the immunity monitoring, estimation of (re)vaccination time, as well as for knowing the factors that should be considered while choosing the most effective vaccine. Finally, several directions for the future research are pointed outVyacheslav S. FedorovOlga N. IvanovaInna L. KarpenkoAlexander V. IvanovEco-vectorarticlecoronavirussars-cov-2immunityantibodiest-cell responseMedicineRRUКлиническая практика , Vol 12, Iss 1, Pp 33-40 (2021)
institution	DOAJ
collection	DOAJ
language	RU
topic	coronavirus sars-cov-2 immunity antibodies t-cell response Medicine R
spellingShingle	coronavirus sars-cov-2 immunity antibodies t-cell response Medicine R Vyacheslav S. Fedorov Olga N. Ivanova Inna L. Karpenko Alexander V. Ivanov The immune response to the novel coronavirus infection
description	This review summarizes the current knowledge on the humoral and T-cell immunity to the novel coronavirus infection. A special attention is paid to the viral proteins that induce production of antibodies, different types of immunoglobulins and their role in the protection against the virus as well as to the duration of the humoral immune response. In addition, a concise analysis of the T-cell immunity status during COVID-19 and its input into the antiviral defense is presented. The collected data demonstrating preservation of both the humoral and T-cell immunity are urgently needed in the medical professionals' community for evidence-based decisions on the immunity monitoring, estimation of (re)vaccination time, as well as for knowing the factors that should be considered while choosing the most effective vaccine. Finally, several directions for the future research are pointed out
format	article
author	Vyacheslav S. Fedorov Olga N. Ivanova Inna L. Karpenko Alexander V. Ivanov
author_facet	Vyacheslav S. Fedorov Olga N. Ivanova Inna L. Karpenko Alexander V. Ivanov
author_sort	Vyacheslav S. Fedorov
title	The immune response to the novel coronavirus infection
title_short	The immune response to the novel coronavirus infection
title_full	The immune response to the novel coronavirus infection
title_fullStr	The immune response to the novel coronavirus infection
title_full_unstemmed	The immune response to the novel coronavirus infection
title_sort	immune response to the novel coronavirus infection
publisher	Eco-vector
publishDate	2021
url	https://doaj.org/article/88bb358e624841668196f2044d9cde44
work_keys_str_mv	AT vyacheslavsfedorov theimmuneresponsetothenovelcoronavirusinfection AT olganivanova theimmuneresponsetothenovelcoronavirusinfection AT innalkarpenko theimmuneresponsetothenovelcoronavirusinfection AT alexandervivanov theimmuneresponsetothenovelcoronavirusinfection AT vyacheslavsfedorov immuneresponsetothenovelcoronavirusinfection AT olganivanova immuneresponsetothenovelcoronavirusinfection AT innalkarpenko immuneresponsetothenovelcoronavirusinfection AT alexandervivanov immuneresponsetothenovelcoronavirusinfection
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The immune response to the novel coronavirus infection

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