Donor-transmitted melanoma after limbal stem cell transplantation

Limbal Stem Cells are a unique cell line located at the corneal limbus. They are responsible for regenerating and restoring corneal epithelial layers. Limbal stem cell transplantation is a promising technique that has been used to treat several hereditary and acquired corneal diseases. Cornea tissue...

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Autores principales: Anas Alsara, Muhammad Rafi
Formato: article
Lenguaje:EN
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2017
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Acceso en línea:https://doaj.org/article/88bd56b375f446e4b350ffe4292109cf
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spelling oai:doaj.org-article:88bd56b375f446e4b350ffe4292109cf2021-12-02T17:58:44ZDonor-transmitted melanoma after limbal stem cell transplantation2231-07702249-446410.4103/2231-0770.203609https://doaj.org/article/88bd56b375f446e4b350ffe4292109cf2017-04-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/2231-0770.203609https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Limbal Stem Cells are a unique cell line located at the corneal limbus. They are responsible for regenerating and restoring corneal epithelial layers. Limbal stem cell transplantation is a promising technique that has been used to treat several hereditary and acquired corneal diseases. Cornea tissue lack vascularity. Hence, there were no special restrictions on collecting ocular tissues from donors with a diagnosis of metastatic melanoma. We are reporting a case of a patient who developed an ocular melanoma after she had limbal stem cell transplantation from a donor with history of melanoma. After this case, Eye Bank Association of America updated the donor criteria to exclude donors with any history of melanoma.Anas AlsaraMuhammad RafiThieme Medical and Scientific Publishers Pvt. Ltd.articledonor-transmitted melanomalimbal stem cell transplanttransplant-related malignancyMedicineRENAvicenna Journal of Medicine, Vol 07, Iss 02, Pp 75-77 (2017)
institution DOAJ
collection DOAJ
language EN
topic donor-transmitted melanoma
limbal stem cell transplant
transplant-related malignancy
Medicine
R
spellingShingle donor-transmitted melanoma
limbal stem cell transplant
transplant-related malignancy
Medicine
R
Anas Alsara
Muhammad Rafi
Donor-transmitted melanoma after limbal stem cell transplantation
description Limbal Stem Cells are a unique cell line located at the corneal limbus. They are responsible for regenerating and restoring corneal epithelial layers. Limbal stem cell transplantation is a promising technique that has been used to treat several hereditary and acquired corneal diseases. Cornea tissue lack vascularity. Hence, there were no special restrictions on collecting ocular tissues from donors with a diagnosis of metastatic melanoma. We are reporting a case of a patient who developed an ocular melanoma after she had limbal stem cell transplantation from a donor with history of melanoma. After this case, Eye Bank Association of America updated the donor criteria to exclude donors with any history of melanoma.
format article
author Anas Alsara
Muhammad Rafi
author_facet Anas Alsara
Muhammad Rafi
author_sort Anas Alsara
title Donor-transmitted melanoma after limbal stem cell transplantation
title_short Donor-transmitted melanoma after limbal stem cell transplantation
title_full Donor-transmitted melanoma after limbal stem cell transplantation
title_fullStr Donor-transmitted melanoma after limbal stem cell transplantation
title_full_unstemmed Donor-transmitted melanoma after limbal stem cell transplantation
title_sort donor-transmitted melanoma after limbal stem cell transplantation
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate 2017
url https://doaj.org/article/88bd56b375f446e4b350ffe4292109cf
work_keys_str_mv AT anasalsara donortransmittedmelanomaafterlimbalstemcelltransplantation
AT muhammadrafi donortransmittedmelanomaafterlimbalstemcelltransplantation
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