CellCycleTRACER accounts for cell cycle and volume in mass cytometry data

Mass cytometry is a powerful method of single cell analysis, but potential confounding effects of cell cycle and cell volume are not taken into account. Here the authors present a combined experimental and computational method to correct for these effects and reveal features of TNFα stimulation that...

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Autores principales: Maria Anna Rapsomaniki, Xiao-Kang Lun, Stefan Woerner, Marco Laumanns, Bernd Bodenmiller, María Rodríguez Martínez
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/88cf8b87f8f24c58a5be08d7dbf1d961
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spelling oai:doaj.org-article:88cf8b87f8f24c58a5be08d7dbf1d9612021-12-02T14:39:05ZCellCycleTRACER accounts for cell cycle and volume in mass cytometry data10.1038/s41467-018-03005-52041-1723https://doaj.org/article/88cf8b87f8f24c58a5be08d7dbf1d9612018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03005-5https://doaj.org/toc/2041-1723Mass cytometry is a powerful method of single cell analysis, but potential confounding effects of cell cycle and cell volume are not taken into account. Here the authors present a combined experimental and computational method to correct for these effects and reveal features of TNFα stimulation that are otherwise masked.Maria Anna RapsomanikiXiao-Kang LunStefan WoernerMarco LaumannsBernd BodenmillerMaría Rodríguez MartínezNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Maria Anna Rapsomaniki
Xiao-Kang Lun
Stefan Woerner
Marco Laumanns
Bernd Bodenmiller
María Rodríguez Martínez
CellCycleTRACER accounts for cell cycle and volume in mass cytometry data
description Mass cytometry is a powerful method of single cell analysis, but potential confounding effects of cell cycle and cell volume are not taken into account. Here the authors present a combined experimental and computational method to correct for these effects and reveal features of TNFα stimulation that are otherwise masked.
format article
author Maria Anna Rapsomaniki
Xiao-Kang Lun
Stefan Woerner
Marco Laumanns
Bernd Bodenmiller
María Rodríguez Martínez
author_facet Maria Anna Rapsomaniki
Xiao-Kang Lun
Stefan Woerner
Marco Laumanns
Bernd Bodenmiller
María Rodríguez Martínez
author_sort Maria Anna Rapsomaniki
title CellCycleTRACER accounts for cell cycle and volume in mass cytometry data
title_short CellCycleTRACER accounts for cell cycle and volume in mass cytometry data
title_full CellCycleTRACER accounts for cell cycle and volume in mass cytometry data
title_fullStr CellCycleTRACER accounts for cell cycle and volume in mass cytometry data
title_full_unstemmed CellCycleTRACER accounts for cell cycle and volume in mass cytometry data
title_sort cellcycletracer accounts for cell cycle and volume in mass cytometry data
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/88cf8b87f8f24c58a5be08d7dbf1d961
work_keys_str_mv AT mariaannarapsomaniki cellcycletraceraccountsforcellcycleandvolumeinmasscytometrydata
AT xiaokanglun cellcycletraceraccountsforcellcycleandvolumeinmasscytometrydata
AT stefanwoerner cellcycletraceraccountsforcellcycleandvolumeinmasscytometrydata
AT marcolaumanns cellcycletraceraccountsforcellcycleandvolumeinmasscytometrydata
AT berndbodenmiller cellcycletraceraccountsforcellcycleandvolumeinmasscytometrydata
AT mariarodriguezmartinez cellcycletraceraccountsforcellcycleandvolumeinmasscytometrydata
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