KSR1- and ERK-dependent translational regulation of the epithelial-to-mesenchymal transition
The epithelial-to-mesenchymal transition (EMT) is considered a transcriptional process that induces a switch in cells from a polarized state to a migratory phenotype. Here, we show that KSR1 and ERK promote EMT-like phenotype through the preferential translation of Epithelial-Stromal Interaction 1 (...
Guardado en:
Autores principales: | Chaitra Rao, Danielle E Frodyma, Siddesh Southekal, Robert A Svoboda, Adrian R Black, Chittibabu Guda, Tomohiro Mizutani, Hans Clevers, Keith R Johnson, Kurt W Fisher, Robert E Lewis |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
eLife Sciences Publications Ltd
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/88d3c636f9184176abf9681d4d5cfcad |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
The Lumen of Human Intestinal Organoids Poses Greater Stress to Bacteria Compared to the Germ-Free Mouse Intestine: <named-content content-type="genus-species">Escherichia coli</named-content> Deficient in RpoS as a Colonization Probe
por: Madeline R. Barron, et al.
Publicado: (2020) -
Rotavirus Infection and Cytopathogenesis in Human Biliary Organoids Potentially Recapitulate Biliary Atresia Development
por: Sunrui Chen, et al.
Publicado: (2020) -
Methodologies for Generating Brain Organoids to Model Viral Pathogenesis in the CNS
por: Hannah K. Hopkins, et al.
Publicado: (2021) -
Stimulation of motilin secretion by bile, free fatty acids, and acidification in human duodenal organoids
por: Emily L. Miedzybrodzka, et al.
Publicado: (2021) -
Assessment of an east-west phenotypic variation in body height, body form and body mass among prehistoric hunter-gatherers of Patagonia and Tierra del Fuego, chile
por: Alfonso-Durruty,Marta, et al.
Publicado: (2017)