Effects of Aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in Wistar rats

A nutritional placebo-controlled study was performed in Wistar rats in order to investigate the effects of 5-weeks aronia juice consumption towards fatty acid (FA) composition of phospholipids in the plasma and liver, as well as plasma glucose (Glu) and cholesterol levels. The animals were divided i...

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Autores principales:	Zec Manja, Debeljak Martačić Jasmina, Ranković Slavica, Pokimica Biljana, Tomić Mirko, Ignjatović Đurđica, Glibetić Maria, Popović Tamara
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2017
Materias:	chokeberry polyphenols low-density lipoprotein arachidonic acid monounsaturated fatty acids Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/88d679badf2849619a6f71f61c30a53d
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spelling	oai:doaj.org-article:88d679badf2849619a6f71f61c30a53d2021-11-17T21:27:51ZEffects of Aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in Wistar rats1820-744810.1515/acve-2017-0010https://doaj.org/article/88d679badf2849619a6f71f61c30a53d2017-03-01T00:00:00Zhttps://doi.org/10.1515/acve-2017-0010https://doaj.org/toc/1820-7448A nutritional placebo-controlled study was performed in Wistar rats in order to investigate the effects of 5-weeks aronia juice consumption towards fatty acid (FA) composition of phospholipids in the plasma and liver, as well as plasma glucose (Glu) and cholesterol levels. The animals were divided into 3 groups of 8 animals each, and randomized to receive either the full polyphenol dose of Aronia melanocarpa juice (AMJ), 4 times less polyphenol dose (¼-AMJ) or polyphenol-lacking placebo beverage (PLB). Each group of 8 male adult Wistar rats received the liquid ad libitum. AMJ decreased the levels of low-density lipoprotein (LDL) (P < 0.05) vs. PLB. AMJ increased dihomo-γ-linoleic acid (DGLA, 20:3n-6) (P < 0.05) and decreased arachidonic acid content (AA, 20:4n-6) (P < 0.05) vs. PLB in liver phospholipids. AMJ significantly increased monounsaturated fatty acids (MUFA) levels both in the liver (P < 0.05) and plasma (P < 0.05). Both aronia juice doses elevated the levels of beneficial n-3 polyunsaturated fatty acids (PUFA) in the plasma and liver. There was a dose-dependent, significant increase (P < 0.001) in cis-vaccenic acid (VA, 18:1n-7) in phospholipids in the plasma and liver. Our results indicate favorable effects of aronia juice intake on lipid parameters in Wistar rats. These findings suggest the potential of aronia dietary intake in cardiometabolic diseases primary prevention strategies in the human population.Zec ManjaDebeljak Martačić JasminaRanković SlavicaPokimica BiljanaTomić MirkoIgnjatović ĐurđicaGlibetić MariaPopović TamaraSciendoarticlechokeberrypolyphenolslow-density lipoproteinarachidonic acidmonounsaturated fatty acidsVeterinary medicineSF600-1100ENActa Veterinaria, Vol 67, Iss 1, Pp 107-120 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	chokeberry polyphenols low-density lipoprotein arachidonic acid monounsaturated fatty acids Veterinary medicine SF600-1100
spellingShingle	chokeberry polyphenols low-density lipoprotein arachidonic acid monounsaturated fatty acids Veterinary medicine SF600-1100 Zec Manja Debeljak Martačić Jasmina Ranković Slavica Pokimica Biljana Tomić Mirko Ignjatović Đurđica Glibetić Maria Popović Tamara Effects of Aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in Wistar rats
description	A nutritional placebo-controlled study was performed in Wistar rats in order to investigate the effects of 5-weeks aronia juice consumption towards fatty acid (FA) composition of phospholipids in the plasma and liver, as well as plasma glucose (Glu) and cholesterol levels. The animals were divided into 3 groups of 8 animals each, and randomized to receive either the full polyphenol dose of Aronia melanocarpa juice (AMJ), 4 times less polyphenol dose (¼-AMJ) or polyphenol-lacking placebo beverage (PLB). Each group of 8 male adult Wistar rats received the liquid ad libitum. AMJ decreased the levels of low-density lipoprotein (LDL) (P < 0.05) vs. PLB. AMJ increased dihomo-γ-linoleic acid (DGLA, 20:3n-6) (P < 0.05) and decreased arachidonic acid content (AA, 20:4n-6) (P < 0.05) vs. PLB in liver phospholipids. AMJ significantly increased monounsaturated fatty acids (MUFA) levels both in the liver (P < 0.05) and plasma (P < 0.05). Both aronia juice doses elevated the levels of beneficial n-3 polyunsaturated fatty acids (PUFA) in the plasma and liver. There was a dose-dependent, significant increase (P < 0.001) in cis-vaccenic acid (VA, 18:1n-7) in phospholipids in the plasma and liver. Our results indicate favorable effects of aronia juice intake on lipid parameters in Wistar rats. These findings suggest the potential of aronia dietary intake in cardiometabolic diseases primary prevention strategies in the human population.
format	article
author	Zec Manja Debeljak Martačić Jasmina Ranković Slavica Pokimica Biljana Tomić Mirko Ignjatović Đurđica Glibetić Maria Popović Tamara
author_facet	Zec Manja Debeljak Martačić Jasmina Ranković Slavica Pokimica Biljana Tomić Mirko Ignjatović Đurđica Glibetić Maria Popović Tamara
author_sort	Zec Manja
title	Effects of Aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in Wistar rats
title_short	Effects of Aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in Wistar rats
title_full	Effects of Aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in Wistar rats
title_fullStr	Effects of Aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in Wistar rats
title_full_unstemmed	Effects of Aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in Wistar rats
title_sort	effects of aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in wistar rats
publisher	Sciendo
publishDate	2017
url	https://doaj.org/article/88d679badf2849619a6f71f61c30a53d
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Effects of Aronia melanocarpa juice on plasma and liver phospholipid fatty acid composition in Wistar rats

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