Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM
The β-barrel assembly machinery (BAM complex) is a key mediator of outer membrane protein biogenesis in Gram-negative bacteria. Here the authors report a cryo-EM structure of the intact BAM complex that suggests that lateral gate opening is a necessary part of the BAM functional cycle.
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Main Authors: | , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2016
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Subjects: | |
Online Access: | https://doaj.org/article/88d9b9184d62412599a6be4be362ef28 |
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Summary: | The β-barrel assembly machinery (BAM complex) is a key mediator of outer membrane protein biogenesis in Gram-negative bacteria. Here the authors report a cryo-EM structure of the intact BAM complex that suggests that lateral gate opening is a necessary part of the BAM functional cycle. |
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