Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells

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Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells

Innate lymphoid cells (ILCs) have been shown to be depleted during HIV-1 infection. Here the authors show that ILC loss is associated with CD4 depletion and gastrointestinal damage in a primate model of SIV infection.

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Detalles Bibliográficos
Autores principales:	Joseph C. Mudd, Kathleen Busman-Sahay, Sarah R. DiNapoli, Stephen Lai, Virginia Sheik, Andrea Lisco, Claire Deleage, Brian Richardson, David J. Palesch, Mirko Paiardini, Mark Cameron, Irini Sereti, R. Keith Reeves, Jacob D. Estes, Jason M. Brenchley
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/88eb33c0a42b444ea1e49cf60a21484e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Descripción
Sumario:	Innate lymphoid cells (ILCs) have been shown to be depleted during HIV-1 infection. Here the authors show that ILC loss is associated with CD4 depletion and gastrointestinal damage in a primate model of SIV infection.