Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells
Innate lymphoid cells (ILCs) have been shown to be depleted during HIV-1 infection. Here the authors show that ILC loss is associated with CD4 depletion and gastrointestinal damage in a primate model of SIV infection.
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Nature Portfolio
2018
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oai:doaj.org-article:88eb33c0a42b444ea1e49cf60a21484e2021-12-02T15:33:44ZHallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells10.1038/s41467-018-05528-32041-1723https://doaj.org/article/88eb33c0a42b444ea1e49cf60a21484e2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05528-3https://doaj.org/toc/2041-1723Innate lymphoid cells (ILCs) have been shown to be depleted during HIV-1 infection. Here the authors show that ILC loss is associated with CD4 depletion and gastrointestinal damage in a primate model of SIV infection.Joseph C. MuddKathleen Busman-SahaySarah R. DiNapoliStephen LaiVirginia SheikAndrea LiscoClaire DeleageBrian RichardsonDavid J. PaleschMirko PaiardiniMark CameronIrini SeretiR. Keith ReevesJacob D. EstesJason M. BrenchleyNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
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Science Q |
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Science Q Joseph C. Mudd Kathleen Busman-Sahay Sarah R. DiNapoli Stephen Lai Virginia Sheik Andrea Lisco Claire Deleage Brian Richardson David J. Palesch Mirko Paiardini Mark Cameron Irini Sereti R. Keith Reeves Jacob D. Estes Jason M. Brenchley Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells |
description |
Innate lymphoid cells (ILCs) have been shown to be depleted during HIV-1 infection. Here the authors show that ILC loss is associated with CD4 depletion and gastrointestinal damage in a primate model of SIV infection. |
format |
article |
author |
Joseph C. Mudd Kathleen Busman-Sahay Sarah R. DiNapoli Stephen Lai Virginia Sheik Andrea Lisco Claire Deleage Brian Richardson David J. Palesch Mirko Paiardini Mark Cameron Irini Sereti R. Keith Reeves Jacob D. Estes Jason M. Brenchley |
author_facet |
Joseph C. Mudd Kathleen Busman-Sahay Sarah R. DiNapoli Stephen Lai Virginia Sheik Andrea Lisco Claire Deleage Brian Richardson David J. Palesch Mirko Paiardini Mark Cameron Irini Sereti R. Keith Reeves Jacob D. Estes Jason M. Brenchley |
author_sort |
Joseph C. Mudd |
title |
Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells |
title_short |
Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells |
title_full |
Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells |
title_fullStr |
Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells |
title_full_unstemmed |
Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells |
title_sort |
hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/88eb33c0a42b444ea1e49cf60a21484e |
work_keys_str_mv |
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