Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells

Innate lymphoid cells (ILCs) have been shown to be depleted during HIV-1 infection. Here the authors show that ILC loss is associated with CD4 depletion and gastrointestinal damage in a primate model of SIV infection.

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Autores principales: Joseph C. Mudd, Kathleen Busman-Sahay, Sarah R. DiNapoli, Stephen Lai, Virginia Sheik, Andrea Lisco, Claire Deleage, Brian Richardson, David J. Palesch, Mirko Paiardini, Mark Cameron, Irini Sereti, R. Keith Reeves, Jacob D. Estes, Jason M. Brenchley
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/88eb33c0a42b444ea1e49cf60a21484e
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spelling oai:doaj.org-article:88eb33c0a42b444ea1e49cf60a21484e2021-12-02T15:33:44ZHallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells10.1038/s41467-018-05528-32041-1723https://doaj.org/article/88eb33c0a42b444ea1e49cf60a21484e2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05528-3https://doaj.org/toc/2041-1723Innate lymphoid cells (ILCs) have been shown to be depleted during HIV-1 infection. Here the authors show that ILC loss is associated with CD4 depletion and gastrointestinal damage in a primate model of SIV infection.Joseph C. MuddKathleen Busman-SahaySarah R. DiNapoliStephen LaiVirginia SheikAndrea LiscoClaire DeleageBrian RichardsonDavid J. PaleschMirko PaiardiniMark CameronIrini SeretiR. Keith ReevesJacob D. EstesJason M. BrenchleyNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Joseph C. Mudd
Kathleen Busman-Sahay
Sarah R. DiNapoli
Stephen Lai
Virginia Sheik
Andrea Lisco
Claire Deleage
Brian Richardson
David J. Palesch
Mirko Paiardini
Mark Cameron
Irini Sereti
R. Keith Reeves
Jacob D. Estes
Jason M. Brenchley
Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells
description Innate lymphoid cells (ILCs) have been shown to be depleted during HIV-1 infection. Here the authors show that ILC loss is associated with CD4 depletion and gastrointestinal damage in a primate model of SIV infection.
format article
author Joseph C. Mudd
Kathleen Busman-Sahay
Sarah R. DiNapoli
Stephen Lai
Virginia Sheik
Andrea Lisco
Claire Deleage
Brian Richardson
David J. Palesch
Mirko Paiardini
Mark Cameron
Irini Sereti
R. Keith Reeves
Jacob D. Estes
Jason M. Brenchley
author_facet Joseph C. Mudd
Kathleen Busman-Sahay
Sarah R. DiNapoli
Stephen Lai
Virginia Sheik
Andrea Lisco
Claire Deleage
Brian Richardson
David J. Palesch
Mirko Paiardini
Mark Cameron
Irini Sereti
R. Keith Reeves
Jacob D. Estes
Jason M. Brenchley
author_sort Joseph C. Mudd
title Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells
title_short Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells
title_full Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells
title_fullStr Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells
title_full_unstemmed Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells
title_sort hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/88eb33c0a42b444ea1e49cf60a21484e
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