Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ
Human T-cell lymphotropic virus type 1 (HTLV-1) is a pathogenic deltaretrovirus. Here the authors resolve the cryo-EM structure of the deltaretroviral intasome in complex with the human host PP2A regulatory subunit.
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Nature Portfolio
2020
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oai:doaj.org-article:88ed9c3bd65c473abff09d401dc534d22021-12-02T19:16:33ZCryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ10.1038/s41467-020-18874-y2041-1723https://doaj.org/article/88ed9c3bd65c473abff09d401dc534d22020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18874-yhttps://doaj.org/toc/2041-1723Human T-cell lymphotropic virus type 1 (HTLV-1) is a pathogenic deltaretrovirus. Here the authors resolve the cryo-EM structure of the deltaretroviral intasome in complex with the human host PP2A regulatory subunit.Michał S. BarskiJordan J. MinnellZuzana HodakovaValerie E. PyeAndrea NansPeter CherepanovGoedele N. MaertensNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020) |
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Science Q Michał S. Barski Jordan J. Minnell Zuzana Hodakova Valerie E. Pye Andrea Nans Peter Cherepanov Goedele N. Maertens Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ |
description |
Human T-cell lymphotropic virus type 1 (HTLV-1) is a pathogenic deltaretrovirus. Here the authors resolve the cryo-EM structure of the deltaretroviral intasome in complex with the human host PP2A regulatory subunit. |
format |
article |
author |
Michał S. Barski Jordan J. Minnell Zuzana Hodakova Valerie E. Pye Andrea Nans Peter Cherepanov Goedele N. Maertens |
author_facet |
Michał S. Barski Jordan J. Minnell Zuzana Hodakova Valerie E. Pye Andrea Nans Peter Cherepanov Goedele N. Maertens |
author_sort |
Michał S. Barski |
title |
Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ |
title_short |
Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ |
title_full |
Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ |
title_fullStr |
Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ |
title_full_unstemmed |
Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ |
title_sort |
cryo-em structure of the deltaretroviral intasome in complex with the pp2a regulatory subunit b56γ |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/88ed9c3bd65c473abff09d401dc534d2 |
work_keys_str_mv |
AT michałsbarski cryoemstructureofthedeltaretroviralintasomeincomplexwiththepp2aregulatorysubunitb56g AT jordanjminnell cryoemstructureofthedeltaretroviralintasomeincomplexwiththepp2aregulatorysubunitb56g AT zuzanahodakova cryoemstructureofthedeltaretroviralintasomeincomplexwiththepp2aregulatorysubunitb56g AT valerieepye cryoemstructureofthedeltaretroviralintasomeincomplexwiththepp2aregulatorysubunitb56g AT andreanans cryoemstructureofthedeltaretroviralintasomeincomplexwiththepp2aregulatorysubunitb56g AT petercherepanov cryoemstructureofthedeltaretroviralintasomeincomplexwiththepp2aregulatorysubunitb56g AT goedelenmaertens cryoemstructureofthedeltaretroviralintasomeincomplexwiththepp2aregulatorysubunitb56g |
_version_ |
1718376924025192448 |