Identification and characterization of a novel botulinum neurotoxin

There are seven well-established types of Botulinum neurotoxins (BoNTs). Here the authors report the identification and characterization of a new type of BoNT—BoNT/X—which cleaves a different site on canonical BoNTs substrates and targets SNARE family members not cleaved by known BoNTs.

Guardado en:

Detalles Bibliográficos
Autores principales:	Sicai Zhang, Geoffrey Masuyer, Jie Zhang, Yi Shen, Daniel Lundin, Linda Henriksson, Shin-Ichiro Miyashita, Markel Martínez-Carranza, Min Dong, Pål Stenmark
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/890984c9d1754f06b679464c60eecc3a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:890984c9d1754f06b679464c60eecc3a
record_format	dspace
spelling	oai:doaj.org-article:890984c9d1754f06b679464c60eecc3a2021-12-02T17:06:00ZIdentification and characterization of a novel botulinum neurotoxin10.1038/ncomms141302041-1723https://doaj.org/article/890984c9d1754f06b679464c60eecc3a2017-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms14130https://doaj.org/toc/2041-1723There are seven well-established types of Botulinum neurotoxins (BoNTs). Here the authors report the identification and characterization of a new type of BoNT—BoNT/X—which cleaves a different site on canonical BoNTs substrates and targets SNARE family members not cleaved by known BoNTs.Sicai ZhangGeoffrey MasuyerJie ZhangYi ShenDaniel LundinLinda HenrikssonShin-Ichiro MiyashitaMarkel Martínez-CarranzaMin DongPål StenmarkNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sicai Zhang Geoffrey Masuyer Jie Zhang Yi Shen Daniel Lundin Linda Henriksson Shin-Ichiro Miyashita Markel Martínez-Carranza Min Dong Pål Stenmark Identification and characterization of a novel botulinum neurotoxin
description	There are seven well-established types of Botulinum neurotoxins (BoNTs). Here the authors report the identification and characterization of a new type of BoNT—BoNT/X—which cleaves a different site on canonical BoNTs substrates and targets SNARE family members not cleaved by known BoNTs.
format	article
author	Sicai Zhang Geoffrey Masuyer Jie Zhang Yi Shen Daniel Lundin Linda Henriksson Shin-Ichiro Miyashita Markel Martínez-Carranza Min Dong Pål Stenmark
author_facet	Sicai Zhang Geoffrey Masuyer Jie Zhang Yi Shen Daniel Lundin Linda Henriksson Shin-Ichiro Miyashita Markel Martínez-Carranza Min Dong Pål Stenmark
author_sort	Sicai Zhang
title	Identification and characterization of a novel botulinum neurotoxin
title_short	Identification and characterization of a novel botulinum neurotoxin
title_full	Identification and characterization of a novel botulinum neurotoxin
title_fullStr	Identification and characterization of a novel botulinum neurotoxin
title_full_unstemmed	Identification and characterization of a novel botulinum neurotoxin
title_sort	identification and characterization of a novel botulinum neurotoxin
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/890984c9d1754f06b679464c60eecc3a
work_keys_str_mv	AT sicaizhang identificationandcharacterizationofanovelbotulinumneurotoxin AT geoffreymasuyer identificationandcharacterizationofanovelbotulinumneurotoxin AT jiezhang identificationandcharacterizationofanovelbotulinumneurotoxin AT yishen identificationandcharacterizationofanovelbotulinumneurotoxin AT daniellundin identificationandcharacterizationofanovelbotulinumneurotoxin AT lindahenriksson identificationandcharacterizationofanovelbotulinumneurotoxin AT shinichiromiyashita identificationandcharacterizationofanovelbotulinumneurotoxin AT markelmartinezcarranza identificationandcharacterizationofanovelbotulinumneurotoxin AT mindong identificationandcharacterizationofanovelbotulinumneurotoxin AT palstenmark identificationandcharacterizationofanovelbotulinumneurotoxin
_version_	1718381741769490432

Identification and characterization of a novel botulinum neurotoxin

Ejemplares similares