Clinical Profile of HLA-B27-Associated Uveitis in an Egyptian Cohort

Eiman Abd El Latif,1 Ahmed Shawkat Abdelhalim2 1Department of Ophthalmology, Faculty of Medicine, Alexandria University, Alexandria, Egypt; 2Department of Ophthalmology, Faculty of Medicine, Minia University, Minia, EgyptCorrespondence: Eiman Abd El LatifDepartment of Ophthalmology, Faculty of Medic...

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Autores principales: Abd El Latif E, Abdelhalim AS
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Publicado: Dove Medical Press 2020
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spelling oai:doaj.org-article:8914b6dd83444feea4a592202b916a112021-12-02T11:13:02ZClinical Profile of HLA-B27-Associated Uveitis in an Egyptian Cohort1177-5483https://doaj.org/article/8914b6dd83444feea4a592202b916a112020-11-01T00:00:00Zhttps://www.dovepress.com/clinical-profile-of-hla-b27-associated-uveitis-in-an-egyptian-cohort-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Eiman Abd El Latif,1 Ahmed Shawkat Abdelhalim2 1Department of Ophthalmology, Faculty of Medicine, Alexandria University, Alexandria, Egypt; 2Department of Ophthalmology, Faculty of Medicine, Minia University, Minia, EgyptCorrespondence: Eiman Abd El LatifDepartment of Ophthalmology, Faculty of Medicine, Alexandria University, 5 Soliman Mahmoud Street, Cleopatra, Alexandria 12311, EgyptTel +20 211 4867-2963Email iman2omar@gmail.comPurpose: To describe the clinical profile of patients with HLA-B27-associated uveitis at 2 Egyptian tertiary eye centers.Methods: A retrospective study reviewing the medical records of all patients with HLA-B27-associated uveitis served at 2 uveitis referral clinics in Egypt between January 2010 and June 2018.Results: The study included a total of 554 patients. Anterior uveitis was the most common type. Ankylosing spondylitis was an important systemic comorbidity in the present study, affecting 27.4% of our patients. Cataract was the most frequent ocular complication. By the conclusion of the study, 6.1% of the affected eyes had a BSCVA poorer than 20/200.Conclusion: The clinical profile of HLA-B27-associated uveitis in our cohort of Egyptian patients is similar to that reported from other regions of the world. In our study, a relatively high rate of cataract was observed.Keywords: Egypt, uveitis, HLA-B27, epidemiology, hypopyonAbd El Latif EAbdelhalim ASDove Medical Pressarticleegyptuveitishla-b27epidemiologyhypopyon.OphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 3821-3828 (2020)
institution DOAJ
collection DOAJ
language EN
topic egypt
uveitis
hla-b27
epidemiology
hypopyon.
Ophthalmology
RE1-994
spellingShingle egypt
uveitis
hla-b27
epidemiology
hypopyon.
Ophthalmology
RE1-994
Abd El Latif E
Abdelhalim AS
Clinical Profile of HLA-B27-Associated Uveitis in an Egyptian Cohort
description Eiman Abd El Latif,1 Ahmed Shawkat Abdelhalim2 1Department of Ophthalmology, Faculty of Medicine, Alexandria University, Alexandria, Egypt; 2Department of Ophthalmology, Faculty of Medicine, Minia University, Minia, EgyptCorrespondence: Eiman Abd El LatifDepartment of Ophthalmology, Faculty of Medicine, Alexandria University, 5 Soliman Mahmoud Street, Cleopatra, Alexandria 12311, EgyptTel +20 211 4867-2963Email iman2omar@gmail.comPurpose: To describe the clinical profile of patients with HLA-B27-associated uveitis at 2 Egyptian tertiary eye centers.Methods: A retrospective study reviewing the medical records of all patients with HLA-B27-associated uveitis served at 2 uveitis referral clinics in Egypt between January 2010 and June 2018.Results: The study included a total of 554 patients. Anterior uveitis was the most common type. Ankylosing spondylitis was an important systemic comorbidity in the present study, affecting 27.4% of our patients. Cataract was the most frequent ocular complication. By the conclusion of the study, 6.1% of the affected eyes had a BSCVA poorer than 20/200.Conclusion: The clinical profile of HLA-B27-associated uveitis in our cohort of Egyptian patients is similar to that reported from other regions of the world. In our study, a relatively high rate of cataract was observed.Keywords: Egypt, uveitis, HLA-B27, epidemiology, hypopyon
format article
author Abd El Latif E
Abdelhalim AS
author_facet Abd El Latif E
Abdelhalim AS
author_sort Abd El Latif E
title Clinical Profile of HLA-B27-Associated Uveitis in an Egyptian Cohort
title_short Clinical Profile of HLA-B27-Associated Uveitis in an Egyptian Cohort
title_full Clinical Profile of HLA-B27-Associated Uveitis in an Egyptian Cohort
title_fullStr Clinical Profile of HLA-B27-Associated Uveitis in an Egyptian Cohort
title_full_unstemmed Clinical Profile of HLA-B27-Associated Uveitis in an Egyptian Cohort
title_sort clinical profile of hla-b27-associated uveitis in an egyptian cohort
publisher Dove Medical Press
publishDate 2020
url https://doaj.org/article/8914b6dd83444feea4a592202b916a11
work_keys_str_mv AT abdellatife clinicalprofileofhlab27associateduveitisinanegyptiancohort
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