Integrated exome and RNA sequencing of TFE3-translocation renal cell carcinoma

Integrated exome and RNA sequencing of TFE3-translocation renal cell carcinoma

TFE3-translocation renal cell carcinoma (TFE3-tRCC) is a rare subtype of kidney cancer with no standard treatment options for the advanced disease. Here, the authors perform genomic and transcriptomic profiling of 63 untreated primary TFE3-tRCC tumours and reveal potential therapeutic targets.

Guardado en:
Detalles Bibliográficos
Autores principales: Guangxi Sun, Junru Chen, Jiayu Liang, Xiaoxue Yin, Mengni Zhang, Jin Yao, Ning He, Cameron M. Armstrong, Linmao Zheng, Xingming Zhang, Sha Zhu, Xiaomeng Sun, Xiaoxia Yang, Wanbin Zhao, Banghua Liao, Xiuyi Pan, Ling Nie, Ling Yang, Yuntian Chen, Jinge Zhao, Haoran Zhang, Jindong Dai, Yali Shen, Jiyan Liu, Rui Huang, Jiandong Liu, Zhipeng Wang, Yuchao Ni, Qiang Wei, Xiang Li, Qiao Zhou, Haojie Huang, Zhenhua Liu, Pengfei Shen, Ni Chen, Hao Zeng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/891d3264bda34fc8b2bddd3474bf72d2
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:891d3264bda34fc8b2bddd3474bf72d2
record_format dspace
spelling oai:doaj.org-article:891d3264bda34fc8b2bddd3474bf72d22021-12-02T19:12:29ZIntegrated exome and RNA sequencing of TFE3-translocation renal cell carcinoma10.1038/s41467-021-25618-z2041-1723https://doaj.org/article/891d3264bda34fc8b2bddd3474bf72d22021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25618-zhttps://doaj.org/toc/2041-1723TFE3-translocation renal cell carcinoma (TFE3-tRCC) is a rare subtype of kidney cancer with no standard treatment options for the advanced disease. Here, the authors perform genomic and transcriptomic profiling of 63 untreated primary TFE3-tRCC tumours and reveal potential therapeutic targets.Guangxi SunJunru ChenJiayu LiangXiaoxue YinMengni ZhangJin YaoNing HeCameron M. ArmstrongLinmao ZhengXingming ZhangSha ZhuXiaomeng SunXiaoxia YangWanbin ZhaoBanghua LiaoXiuyi PanLing NieLing YangYuntian ChenJinge ZhaoHaoran ZhangJindong DaiYali ShenJiyan LiuRui HuangJiandong LiuZhipeng WangYuchao NiQiang WeiXiang LiQiao ZhouHaojie HuangZhenhua LiuPengfei ShenNi ChenHao ZengNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Guangxi Sun
Junru Chen
Jiayu Liang
Xiaoxue Yin
Mengni Zhang
Jin Yao
Ning He
Cameron M. Armstrong
Linmao Zheng
Xingming Zhang
Sha Zhu
Xiaomeng Sun
Xiaoxia Yang
Wanbin Zhao
Banghua Liao
Xiuyi Pan
Ling Nie
Ling Yang
Yuntian Chen
Jinge Zhao
Haoran Zhang
Jindong Dai
Yali Shen
Jiyan Liu
Rui Huang
Jiandong Liu
Zhipeng Wang
Yuchao Ni
Qiang Wei
Xiang Li
Qiao Zhou
Haojie Huang
Zhenhua Liu
Pengfei Shen
Ni Chen
Hao Zeng
Integrated exome and RNA sequencing of TFE3-translocation renal cell carcinoma
description TFE3-translocation renal cell carcinoma (TFE3-tRCC) is a rare subtype of kidney cancer with no standard treatment options for the advanced disease. Here, the authors perform genomic and transcriptomic profiling of 63 untreated primary TFE3-tRCC tumours and reveal potential therapeutic targets.
format article
author Guangxi Sun
Junru Chen
Jiayu Liang
Xiaoxue Yin
Mengni Zhang
Jin Yao
Ning He
Cameron M. Armstrong
Linmao Zheng
Xingming Zhang
Sha Zhu
Xiaomeng Sun
Xiaoxia Yang
Wanbin Zhao
Banghua Liao
Xiuyi Pan
Ling Nie
Ling Yang
Yuntian Chen
Jinge Zhao
Haoran Zhang
Jindong Dai
Yali Shen
Jiyan Liu
Rui Huang
Jiandong Liu
Zhipeng Wang
Yuchao Ni
Qiang Wei
Xiang Li
Qiao Zhou
Haojie Huang
Zhenhua Liu
Pengfei Shen
Ni Chen
Hao Zeng
author_facet Guangxi Sun
Junru Chen
Jiayu Liang
Xiaoxue Yin
Mengni Zhang
Jin Yao
Ning He
Cameron M. Armstrong
Linmao Zheng
Xingming Zhang
Sha Zhu
Xiaomeng Sun
Xiaoxia Yang
Wanbin Zhao
Banghua Liao
Xiuyi Pan
Ling Nie
Ling Yang
Yuntian Chen
Jinge Zhao
Haoran Zhang
Jindong Dai
Yali Shen
Jiyan Liu
Rui Huang
Jiandong Liu
Zhipeng Wang
Yuchao Ni
Qiang Wei
Xiang Li
Qiao Zhou
Haojie Huang
Zhenhua Liu
Pengfei Shen
Ni Chen
Hao Zeng
author_sort Guangxi Sun
title Integrated exome and RNA sequencing of TFE3-translocation renal cell carcinoma
title_short Integrated exome and RNA sequencing of TFE3-translocation renal cell carcinoma
title_full Integrated exome and RNA sequencing of TFE3-translocation renal cell carcinoma
title_fullStr Integrated exome and RNA sequencing of TFE3-translocation renal cell carcinoma
title_full_unstemmed Integrated exome and RNA sequencing of TFE3-translocation renal cell carcinoma
title_sort integrated exome and rna sequencing of tfe3-translocation renal cell carcinoma
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/891d3264bda34fc8b2bddd3474bf72d2
work_keys_str_mv AT guangxisun integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT junruchen integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT jiayuliang integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT xiaoxueyin integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT mengnizhang integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT jinyao integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT ninghe integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT cameronmarmstrong integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT linmaozheng integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT xingmingzhang integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT shazhu integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT xiaomengsun integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT xiaoxiayang integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT wanbinzhao integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT banghualiao integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT xiuyipan integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT lingnie integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT lingyang integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT yuntianchen integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT jingezhao integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT haoranzhang integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT jindongdai integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT yalishen integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT jiyanliu integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT ruihuang integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT jiandongliu integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT zhipengwang integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT yuchaoni integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT qiangwei integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT xiangli integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT qiaozhou integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT haojiehuang integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT zhenhualiu integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT pengfeishen integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT nichen integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
AT haozeng integratedexomeandrnasequencingoftfe3translocationrenalcellcarcinoma
_version_ 1718377054546690048

Ejemplares similares