3-D vascularized breast cancer model to study the role of osteoblast in formation of a pre-metastatic niche

Abstract Breast cancer cells (BCCs) preferentially metastasize to bone. It is known that BCCs remotely primes the distant bone site prior to metastasis. However, the reciprocal influence of bone cells on the primary tumor is relatively overlooked. Here, to study the bone-tumor paracrine influence, a...

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Autores principales: Rahul Rimal, Prachi Desai, Andrea Bonnin Marquez, Karina Sieg, Yvonne Marquardt, Smriti Singh
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/891eee49a07947a5b73538b12c5dbd68
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