Fungal Septic Knee Arthritis Caused by <i>Aspergillus fumigatus</i> following Anterior Cruciate Ligament Reconstruction

Postoperative infections after arthroscopic anterior cruciate ligament (ACL) reconstruction (ACLR) represent a rare but severe complication. An extremely rare case of <i>Aspergillus</i> septic arthritis in a 27-year-old patient following arthroscopic ACLR is reported. The patient present...

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Autores principales:	George Samonis, Christos Koutserimpas, Georgia Vrioni, Elsa Kampos Martinez, Panagiotis Kouloumentas, Kalliopi Alpantaki, George Saroglou
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	<i>Aspergillus</i> arthritis fungal arthritis knee infection anterior cruciate ligament infection Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/89276fc4032b43038b3ecf52f47cc2f2
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spelling	oai:doaj.org-article:89276fc4032b43038b3ecf52f47cc2f22021-11-25T17:20:23ZFungal Septic Knee Arthritis Caused by <i>Aspergillus fumigatus</i> following Anterior Cruciate Ligament Reconstruction10.3390/diagnostics111119752075-4418https://doaj.org/article/89276fc4032b43038b3ecf52f47cc2f22021-10-01T00:00:00Zhttps://www.mdpi.com/2075-4418/11/11/1975https://doaj.org/toc/2075-4418Postoperative infections after arthroscopic anterior cruciate ligament (ACL) reconstruction (ACLR) represent a rare but severe complication. An extremely rare case of <i>Aspergillus</i> septic arthritis in a 27-year-old patient following arthroscopic ACLR is reported. The patient presented with signs of knee infection 14 days after ACLR. Two consecutive arthroscopic debridements were performed, while eventually histopathology, cultures and multiplex PCR test revealed <i>Aspergillus</i> identified as <i>A. fumigatus</i> by mass spectrometry. The patient commenced long-term treatment with voriconazole. Fungal arthritis or osteomyelitis following ACLR has a mild local and general inflammatory reaction when compared to the bacterial ones. Nevertheless, such infections may lead to aggressive osseous destruction and necrosis. A high index of suspicion is of utmost importance for early detection, while microscopic, histological examination and multiplex PCR may be more helpful for the diagnosis than cultures since cultures are more time-consuming and may vary depending on different factors.George SamonisChristos KoutserimpasGeorgia VrioniElsa Kampos MartinezPanagiotis KouloumentasKalliopi AlpantakiGeorge SaroglouMDPI AGarticle<i>Aspergillus</i> arthritisfungal arthritisknee infectionanterior cruciate ligament infectionMedicine (General)R5-920ENDiagnostics, Vol 11, Iss 1975, p 1975 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	<i>Aspergillus</i> arthritis fungal arthritis knee infection anterior cruciate ligament infection Medicine (General) R5-920
spellingShingle	<i>Aspergillus</i> arthritis fungal arthritis knee infection anterior cruciate ligament infection Medicine (General) R5-920 George Samonis Christos Koutserimpas Georgia Vrioni Elsa Kampos Martinez Panagiotis Kouloumentas Kalliopi Alpantaki George Saroglou Fungal Septic Knee Arthritis Caused by <i>Aspergillus fumigatus</i> following Anterior Cruciate Ligament Reconstruction
description	Postoperative infections after arthroscopic anterior cruciate ligament (ACL) reconstruction (ACLR) represent a rare but severe complication. An extremely rare case of <i>Aspergillus</i> septic arthritis in a 27-year-old patient following arthroscopic ACLR is reported. The patient presented with signs of knee infection 14 days after ACLR. Two consecutive arthroscopic debridements were performed, while eventually histopathology, cultures and multiplex PCR test revealed <i>Aspergillus</i> identified as <i>A. fumigatus</i> by mass spectrometry. The patient commenced long-term treatment with voriconazole. Fungal arthritis or osteomyelitis following ACLR has a mild local and general inflammatory reaction when compared to the bacterial ones. Nevertheless, such infections may lead to aggressive osseous destruction and necrosis. A high index of suspicion is of utmost importance for early detection, while microscopic, histological examination and multiplex PCR may be more helpful for the diagnosis than cultures since cultures are more time-consuming and may vary depending on different factors.
format	article
author	George Samonis Christos Koutserimpas Georgia Vrioni Elsa Kampos Martinez Panagiotis Kouloumentas Kalliopi Alpantaki George Saroglou
author_facet	George Samonis Christos Koutserimpas Georgia Vrioni Elsa Kampos Martinez Panagiotis Kouloumentas Kalliopi Alpantaki George Saroglou
author_sort	George Samonis
title	Fungal Septic Knee Arthritis Caused by <i>Aspergillus fumigatus</i> following Anterior Cruciate Ligament Reconstruction
title_short	Fungal Septic Knee Arthritis Caused by <i>Aspergillus fumigatus</i> following Anterior Cruciate Ligament Reconstruction
title_full	Fungal Septic Knee Arthritis Caused by <i>Aspergillus fumigatus</i> following Anterior Cruciate Ligament Reconstruction
title_fullStr	Fungal Septic Knee Arthritis Caused by <i>Aspergillus fumigatus</i> following Anterior Cruciate Ligament Reconstruction
title_full_unstemmed	Fungal Septic Knee Arthritis Caused by <i>Aspergillus fumigatus</i> following Anterior Cruciate Ligament Reconstruction
title_sort	fungal septic knee arthritis caused by <i>aspergillus fumigatus</i> following anterior cruciate ligament reconstruction
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/89276fc4032b43038b3ecf52f47cc2f2
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Fungal Septic Knee Arthritis Caused by <i>Aspergillus fumigatus</i> following Anterior Cruciate Ligament Reconstruction

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