Outcomes of Roux-en-Y gastric bypass surgery for severely obese patients with type 1 diabetes: a case series report

Carlos E Mendez, Robert J Tanenberg, Walter PoriesDiabetes and Obesity Institute, East Carolina University, Greenville, NC, USAAbstract: Roux-en-Y gastric bypass surgery (RYGB) reverses type 2 diabetes (DM2) in approximately 83% of patients with morbid or severe obesity. This procedure has been perf...

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Autores principales:	Tanenberg RJ, Pories WJ
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Bariatric Surgery Gastric Bypass Type 1 Diabetes Severe Obesity Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/892842cd56454a699ee2ea9bf846a8ca
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spelling	oai:doaj.org-article:892842cd56454a699ee2ea9bf846a8ca2021-12-02T07:09:29ZOutcomes of Roux-en-Y gastric bypass surgery for severely obese patients with type 1 diabetes: a case series report1178-7007https://doaj.org/article/892842cd56454a699ee2ea9bf846a8ca2010-08-01T00:00:00Zhttps://www.dovepress.com/outcomes-of-roux-en-y-gastric-bypass-surgery-for-severely-obese-patien-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Carlos E Mendez, Robert J Tanenberg, Walter PoriesDiabetes and Obesity Institute, East Carolina University, Greenville, NC, USAAbstract: Roux-en-Y gastric bypass surgery (RYGB) reverses type 2 diabetes (DM2) in approximately 83% of patients with morbid or severe obesity. This procedure has been performed in small numbers of severely obese patients with type 1 diabetes (DM1), but the impact on glycemic control and insulin requirement in this population has not been widely described. We report three patients with DM1 and severe obesity that underwent RYGB. Weight, glycemic control, and insulin requirements before and one year after the procedure were compared. Significant weight loss was achieved by all three patients but insulin requirements decreased in only 2 patients. In contrast, glycemic control (A1C) remained suboptimal in all three patients up to one year after the surgery. These findings suggest that RYGB leads to important weight loss and positively affects insulin sensitivity. However, reaching optimal glycemic control in patients with DM1 diabetes remains challenging due to persisting insulin deficiency.Keywords: gastric bypass, Roux-en-Y, obesity, diabetes, insulinTanenberg RJTanenberg RJPories WJDove Medical PressarticleBariatric SurgeryGastric BypassType 1 DiabetesSevere ObesitySpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 3, Pp 281-283 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Bariatric Surgery Gastric Bypass Type 1 Diabetes Severe Obesity Specialties of internal medicine RC581-951
spellingShingle	Bariatric Surgery Gastric Bypass Type 1 Diabetes Severe Obesity Specialties of internal medicine RC581-951 Tanenberg RJ Tanenberg RJ Pories WJ Outcomes of Roux-en-Y gastric bypass surgery for severely obese patients with type 1 diabetes: a case series report
description	Carlos E Mendez, Robert J Tanenberg, Walter PoriesDiabetes and Obesity Institute, East Carolina University, Greenville, NC, USAAbstract: Roux-en-Y gastric bypass surgery (RYGB) reverses type 2 diabetes (DM2) in approximately 83% of patients with morbid or severe obesity. This procedure has been performed in small numbers of severely obese patients with type 1 diabetes (DM1), but the impact on glycemic control and insulin requirement in this population has not been widely described. We report three patients with DM1 and severe obesity that underwent RYGB. Weight, glycemic control, and insulin requirements before and one year after the procedure were compared. Significant weight loss was achieved by all three patients but insulin requirements decreased in only 2 patients. In contrast, glycemic control (A1C) remained suboptimal in all three patients up to one year after the surgery. These findings suggest that RYGB leads to important weight loss and positively affects insulin sensitivity. However, reaching optimal glycemic control in patients with DM1 diabetes remains challenging due to persisting insulin deficiency.Keywords: gastric bypass, Roux-en-Y, obesity, diabetes, insulin
format	article
author	Tanenberg RJ Tanenberg RJ Pories WJ
author_facet	Tanenberg RJ Tanenberg RJ Pories WJ
author_sort	Tanenberg RJ
title	Outcomes of Roux-en-Y gastric bypass surgery for severely obese patients with type 1 diabetes: a case series report
title_short	Outcomes of Roux-en-Y gastric bypass surgery for severely obese patients with type 1 diabetes: a case series report
title_full	Outcomes of Roux-en-Y gastric bypass surgery for severely obese patients with type 1 diabetes: a case series report
title_fullStr	Outcomes of Roux-en-Y gastric bypass surgery for severely obese patients with type 1 diabetes: a case series report
title_full_unstemmed	Outcomes of Roux-en-Y gastric bypass surgery for severely obese patients with type 1 diabetes: a case series report
title_sort	outcomes of roux-en-y gastric bypass surgery for severely obese patients with type 1 diabetes: a case series report
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/892842cd56454a699ee2ea9bf846a8ca
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Outcomes of Roux-en-Y gastric bypass surgery for severely obese patients with type 1 diabetes: a case series report

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