Proteoglycans contribute to the functional integrity of the glomerular endothelial cell surface layer and are regulated in diabetic kidney disease
Abstract All capillary endothelia, including those of the glomeruli, have a luminal cell surface layer (ESL) consisting of glycoproteins, glycolipids, proteoglycans (PGs) and glycosaminoglycans. Previous results have demonstrated that an intact ESL is necessary for a normal filtration barrier and da...
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Autores principales: | Alina Khramova, Roberto Boi, Vincent Fridén, Anna Björnson Granqvist, Ulf Nilsson, Olav Tenstad, Eystein Oveland, Börje Haraldsson, Kerstin Ebefors, Jenny Nyström |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/893469d74f4a4c3aa2e23c7c29efebb4 |
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