Proteoglycans contribute to the functional integrity of the glomerular endothelial cell surface layer and are regulated in diabetic kidney disease
Abstract All capillary endothelia, including those of the glomeruli, have a luminal cell surface layer (ESL) consisting of glycoproteins, glycolipids, proteoglycans (PGs) and glycosaminoglycans. Previous results have demonstrated that an intact ESL is necessary for a normal filtration barrier and da...
Enregistré dans:
Auteurs principaux: | Alina Khramova, Roberto Boi, Vincent Fridén, Anna Björnson Granqvist, Ulf Nilsson, Olav Tenstad, Eystein Oveland, Börje Haraldsson, Kerstin Ebefors, Jenny Nyström |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/893469d74f4a4c3aa2e23c7c29efebb4 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
The Glomerular Endothelium Restricts Albumin Filtration
par: Barbara J. Ballermann, et autres
Publié: (2021) -
Effects of melanocortin 1 receptor agonists in experimental nephropathies.
par: Annika Lindskog Jonsson, et autres
Publié: (2014) -
Glomerular endothelial cell heterogeneity in Alport syndrome
par: Hasmik Soloyan, et autres
Publié: (2020) -
Glomerular endothelial cell senescence drives age‐related kidney disease through PAI‐1
par: Camille Cohen, et autres
Publié: (2021) -
Heparan sulfate proteoglycan glypican-1 and PECAM-1 cooperate in shear-induced endothelial nitric oxide production
par: Anne Marie W. Bartosch, et autres
Publié: (2021)